2025 NFL Defensive Player of the Year Odds and Predictions: Favorites, Sleepers and Best Bets

NFL Defensive Player of the Year Odds and Betting Advice For The 2025 Season!

Sportsmemo’s Steve Seagrave gives 2025 NFL Defensive Player of the Year odds, picks and predictions including sleepers on who will lift the hardware come the end of the season! Which players have the best odds to win?

What are some key NFL Defensive Player of the Year betting trends to keep an eye on? Get Steve’s NFL Defensive Player of the Year picks and predictions below!

2025 NFL Defensive Player of the Year Odds (DraftKings)

Past NFL Defensive Player of the Year Winners

NFL Defensive Player of the Year Betting Trends

Last season, Denver Broncos cornerback Patrick Surtain II became just the second defensive back to win the award since 2010 (Stephon Gilmore 2019).

Surtain intercepted four passes, with 11 passes defended, a forced fumble, a recovery and a tackle for a loss in 16 starts.

However, sacks are one of the easiest quantifiable statistics for a defensive player to show value to their team.

So, it makes sense that all of the favorites to win the award are pass rushers. The award has been won by defensive linemen or edge rushers in 11 of the past 14 seasons.

Myles Garrett won the DPOY in 2023 after finishing top 10 in every notable category including sacks, QB hits, tackles for a loss, QB pressures and forced fumbles. 

Nick Bosa won the award in 2022 after an 18.5 sack season while TJ Watt got DPOY honors after a 21.5 sack campaign in 2021.

Micah Parsons has flirted with the award, finishing as the runner-up in two of his first three seasons in the NFL. Aaron Donald brought home DPOY honors three times in his amazing stretch with the Rams.

2025 NFL Defensive Player of the Year Prediction: Aidan Hutchinson, Lions (+650)

A gruesome leg ended Aidan Hutchinsons 2024 campaign after only five games, but he’s back on the field with the Detroit Lions training camp with no restrictions and his play has impressed new defensive coordinator Kelvin Sheppard. 

Sheppard has been with the Lions defensive staff since 2021, so he’s seen Hutchinsons development, and he’s convinced the experience made Hutchinson a better player. 

Hutchinson looked like he would be in contention to win this award before fracturing his leg as he logged 7.5 sacks in five games, giving him 28.5 sacks in 39 career games. 

The 24-year-old is also very effective in coverage as he’s logged four interceptions in his shortened three-year career. 

Hutchinson is actually listed among the favorites to win the Comeback Player of the Year which is rare for a defensive player.

The Lions are looking to build on a stellar 15-2 season, and they only team with better odds of winning the NFC are the Superbowl champion Philadelphia Eagles.

If Hutchinson stays healthy, he will surely be on voter’s radars as a crucial part of championship-caliber defense.

2025 Defensive Player of the Year Sleeper Prediction: Will Anderson, Texans (+1300)

It feels like any one of the top 5 favorites could easily win this award and at +1300 Will Anderson has the best value.

Pass rushers have dominated this award, and Anderson recorded 11 sacks last season despite playing only 14 games and he now has 18 sacks through just 29 career games.

The 2023 Defensive Rookie of the Year now has a career 15.3 % pressure rate and that would have ranked 9th among qualifying pass rushers last season.

Houston Texans head coach DeMeco Ryans utilizes a very aggressive scheme that prioritizes pressure so Anderson could approach the 20-sack mark.

Playing with another elite edge rusher in Danielle Hunter could hurt Anderson’s case but it could also help him avoid double teams and post huge numbers.

The Texans are the odd-on favorite to win the AFC South and that could help draw voters’ attention to Anderson as Houston’s designated defensive playmaker.

Other 2025 NFL Futures Picks Below

2025 NFL MVP Award

2025 NFL Offensive Player of the Year Award

2025 NFL Offensive Rookie of the Year Award

2025 NFL Defensive Rookie of the Year Award

2025 NFL Coach of the Year Award

2025 NFL Comeback Player of the Year Award

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