West Virginia vs BYU Predictions and Picks | Friday College Football Week 6 Betting Preview

West Virginia battles BYU in a Big 12 showdown for Friday College Football Week 6! With the Cougars favored by nearly three touchdowns they look to keep their undefeated record in tact while facing a feisty Mountaineers team that has lost two straight games. Get a betting preview from The GoldSheet for college football week 6 West Virginia vs BYU below!

West Virginia vs BYU Betting Preview

Date and Time	October 3, 2025 at 10:30PM ET
Point Spread	BYU -19.5
Total (Over/Under)	47.5
Location	LaVell Edwards Stadium in Provo, UT
TV	ESPN
Forecast	Warm and Clear

West Virginia vs BYU Recent Head-to-Head Results

West Virginia enters this matchup with a brief but successful history against BYU. The two programs have met only twice before, and in both games, the Mountaineers secured victories while also covering the spread.

The most recent meeting came in November 2023, when West Virginia dominated at home in Morgantown.

That contest ended in a 37-7 result, with the Mountaineers controlling the action throughout. While that history gives West Virginia some confidence, the circumstances heading into this year’s game look quite different.

West Virginia’s Recent Form

The Mountaineers’ second game of the season was an emotional overtime win against long-time rival Pittsburgh in the Backyard Brawl.

That victory served as a high point and suggested West Virginia might carry positive momentum into the following weeks. Unfortunately, the opposite has occurred.

Since that overtime triumph, West Virginia has been outscored 89-24 in consecutive blowout losses to Utah and Kansas.

Both games quickly got away from them, and the inability to remain competitive has raised concerns about whether the Mountaineers can adjust and steady themselves against stronger opponents.

West Virginia’s Quarterback Situation

Complicating matters further for West Virginia is the loss of starting quarterback Nicco Marchiol. He has been officially ruled out due to a foot injury.

Losing the starter in the middle of a season is never ideal, but it is especially challenging for a team already struggling to find consistency.

A backup quarterback will now be tasked with leading the offense in a difficult road environment. While the coaching staff will work to prepare the replacement, the lack of experience and established rhythm compared to Marchiol could have a significant impact on West Virginia’s ability to move the ball effectively.

BYU’s Strong Start

The Cougars enter this matchup in sharp contrast to their opponent. BYU is undefeated at 4-0 straight up and has rewarded bettors with a 3-1 record against the spread.

The team has displayed balance in all phases of the game, which has allowed them to handle a variety of challenges through the first month of the season.

Adding intrigue to this contest is the fact that it will be BYU’s first home game in almost a month. After back-to-back road trips to East Carolina and Colorado, followed by a bye week, the Cougars finally return to LaVell Edwards Stadium.

The home-field advantage in Provo has long been a key element for BYU, and the crowd is expected to give the Cougars an energy boost after their extended stretch away.

Coaching and Pace of Play

West Virginia head coach Rich Rodriguez is well known for his up-tempo offensive philosophy. Throughout his career, his teams have emphasized speed, spread formations, and quick strikes to keep defenses unsettled.

However, in this particular game, that approach may not be the wisest option. Playing at a fast pace with a backup quarterback increases the risk of errors and quick possessions ending in punts.

That scenario would only put more pressure on a defense that has already allowed large scoring totals in recent outings.

Adjusting to a more deliberate tempo, managing possessions, and limiting mistakes could give West Virginia a better chance to remain competitive.

West Virginia vs BYU Prediction: Under 47.5

One of the most notable patterns surrounding BYU’s season so far has been the performance of the total. Each of the Cougars’ last three games has stayed under the posted number. Whether that is due to solid defense, a measured offensive approach, or a blend of both, the result has been consistent.

That trend is worth monitoring again in this matchup. With West Virginia turning to a backup quarterback on the road and BYU’s recent track record of unders, the total once again feels like the most relevant angle to watch.

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