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San Diego State vs Grand Canyon Prediction and Picks โ€“ January 21 2026

San Diego State vs Grand Canyon - January 21, 2026

The college basketball season continues Wednesday night with a fascinating San Diego State vs Grand Canyon mid-major matchup. This matchup is crucial for the Mountain West Conference standings with the Aztecs riding seven straight wins.

Grand Canyon has won three of their last four games with two of those coming on the road as they continue to showcase their talents in the Mountain West Conference.

The storyline surrounding this game adds a layer of familiarity and strategy that makes it one of the more compelling mid-season contests. Free picks and predictions from The GoldSheet below!

A Familiar Opponent for San Diego State

This is the first meeting between the Aztecs and Antelopes since Grand Canyon moved to the Mountain West, but they do have some recent familiarity with one another.

Grand Canyon beat San Diego State in Phoenix in December 2023, and the ‘Lopes have gotten off to a great start in their first season in the Mountain West. 

San Diego State & Grand Canyon Recent Form

Bryce Drew’s squad handed Utah State its second loss of the season on Saturday to improve to 4-2 in conference play.

San Diego State has won seven in a row, but the Aztecs are making this trek to Phoenix without seven-foot center Magoon Gwath.

The sophomore has averaged 2.2 blocks per game during his career and is one of the best interior defenders in the conference.

Gwath was only able to play ten minutes on Saturday against New Mexico and his absence was immediately felt.

San Diego State took a 13-point lead into halftime against the Lobos, but they gave up 44 points in the second half when Gwath was out of the game.

We are interested in the over in this contest. The Aztecs are playing much faster than any other SDSU team during the Brian Dutcher era.

San Diego State vs Grand Canyon Prediction: Over 143.5

San Diego State is only using an average of 16.5 seconds per possession, compared to 18.1 seconds last year.

Since they don’t have to wait for a seven-footer to travel the length of the court, the Aztecs are now free to play even faster if they choose to do so.

Conference opponents have only hit 27.6-percent from the three-point line against Grand Canyon’s defense, but San Diego State has shooters that can put a stop to that.

The Aztecs are top-25 in three-point shooting, hitting over 37-percent from beyond the arc this season. Both teams are good from the free throw line. We’re expecting to see some points in this one.

GoldSheet Top Picks

Whether you enjoy written analysis, breaking down stats or creating your own power ratings, The Basketball GoldSheet has something for everyone.

The Basketball GoldSheet newsletter features stat breakdowns for every NBA and college basketball game each day, plus in-depth written analysis on our Key Releases by 12pm ET / 9am PT each morning.

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