Trail Blazers vs Lakers Predictions, Picks and Odds

The last time these teams met, the Lakers shot 56.3% from the field, knocked down 17 three-pointers at home, and still lost by seven. Portland has now won four of the last five meetings and covered in every one of those wins, and the Blazers arrive in Los Angeles riding a three-game win-and-cover streak on this road trip.

The Lakers have been hot too, but the matchup history and Portland’s depth tell a compelling story. With the spread hovering between 2.5 and 3.5, this Trail Blazers vs Lakers rematch is one of the best underdog spots on the NBA board. Before you lock in your NBA picks, here is the full breakdown of the odds, line movement, matchups, and best bets.

Trail Blazers vs Lakers Quick Picks and Prediction

Spread Pick: Trail Blazers +2.5 (-101)
Moneyline Pick: Portland Trail Blazers
Total Pick: Over 231.5 (-105)
Projected Final Score: Trail Blazers 121, Lakers 117

Odds and Line Movement for Trail Blazers vs Lakers

Los Angeles opened as a 2.5-point favorite and has bounced between -2.5 and -3.5 throughout the morning, currently sitting at -2.5 with heavy -119 juice. The public has been split, with Portland drawing 54% of the money. The total opened at 233.5 and has drifted down to 231.5, with 75% of the money on the under but a majority of tickets on the over. Shop the latest odds for the best number, as +3.5 has been available at times.

Opening Odds

Team	Spread	Total
Portland Trail Blazers	+2.5 (-114)	Over 233.5 (-114)
Los Angeles Lakers	-2.5 (-106)	Under 233.5 (-106)

Current Odds

Team	Spread	Total
Portland Trail Blazers	+2.5 (-101)	Over 231.5 (-105)
Los Angeles Lakers	-2.5 (-119)	Under 231.5 (-115)

Line Movement – Spread

Date	Portland	L.A. Lakers	Public ($, #)
11/06	+2.5 (-101)	-2.5 (-119)	POR 54%, POR 50%
11/06	+3.5 (-120)	-3.5 (-101)	POR 54%, POR 50%
11/06	+2.5 (-102)	-2.5 (-119)	POR 54%, POR 50%
11/06	+3.5 (-119)	-3.5 (-101)	POR 54%, POR 50%
11/06	+2.5 (-103)	-2.5 (-118)	POR 54%, LAL 53%
11/06	+3.5 (-118)	-3.5 (-102)	POR 54%, LAL 56%
11/06	+2.5 (-102)	-2.5 (-119)	POR 54%, LAL 56%
11/06	+3.5 (-119)	-3.5 (-102)	POR 54%, LAL 56%
11/06	+2.5 (-105)	-2.5 (-115)	—
11/05	+2.5 (-114)	-2.5 (-106)	—

Line Movement – Total

Date	Over	Under	Public ($, #)
11/06	231.5 (-105)	231.5 (-115)	UN 75%, OV 63%
11/06	231.5 (-109)	231.5 (-110)	UN 75%, OV 63%
11/06	232.5 (-105)	232.5 (-115)	UN 56%, OV 73%
11/06	231.5 (-115)	231.5 (-105)	UN 56%, OV 73%
11/06	232.5 (-105)	232.5 (-115)	UN 57%, OV 75%
11/06	231.5 (-114)	231.5 (-106)	UN 57%, OV 75%
11/06	232.5 (-106)	232.5 (-114)	UN 57%, OV 75%
11/06	231.5 (-112)	231.5 (-108)	UN 57%, OV 75%
11/06	232.5 (-107)	232.5 (-113)	UN 77%, OV 67%
11/06	233.5 (-105)	233.5 (-115)	UN 77%, OV 67%
11/06	232.5 (-115)	232.5 (-105)	UN 77%, OV 67%
11/05	233.5 (-114)	233.5 (-106)	—

Key Matchups and Handicap: Trail Blazers vs Lakers

Portland is 4-1 straight-up and against the spread over the last five meetings in this Western Conference matchup, including a 136-129 road win in Los Angeles on October 27. Each of the last four meetings has gone over the total, averaging 245.3 combined points. Both teams enter in strong form, but Portland’s depth and recent success in this matchup give it the edge.

Blazers Rolling on the Road

This is the fourth game of a road trip for the Blazers, who have won and covered each of the first three against the Jazz, Nuggets, and Suns. Portland is on the front end of a back-to-back and heads home to host the Spurs on Saturday. That look-ahead spot is a slight concern, but the Blazers should put everything into tonight’s game against an opponent they have handled well.

Portland Has Depth to Burn

Four Blazers finished the first meeting with 20 or more points. Portland has plenty of players capable of filling the stat sheet on any given night, and that balance makes the Blazers difficult to game-plan for. It also helped them overcome a Lakers team that shot 56.3% from the field and made 17 three-pointers in that game.

Lakers Riding a Hot Streak

The purple and gold have been kind to bettors over the last week. Since that loss to Portland, the Lakers have gone 4-1 straight-up and against the spread, including back-to-back double-digit wins over the Heat and Kings. Los Angeles is playing well, but its recent opponents have not posed the same matchup problems Portland does.

Los Angeles Leans on Doncic and Reaves

The key question for Los Angeles is depth. Outside of Luka Doncic and Austin Reaves, can the Lakers consistently count on other players to fill the stat sheet the way Portland can? If the Blazers spread the scoring again, the Lakers’ top-heavy attack may struggle to keep pace.

POR vs LAL Betting Trends

Portland is 4-1 SU and ATS over the last five meetings with the Lakers.
Portland won 136-129 in Los Angeles on October 27.
Each of the last four meetings has gone over the total, averaging 245.3 points.
Portland has won and covered each of the first three games of this road trip.
The Lakers are 4-1 SU and ATS since losing to Portland.
The spread has moved between Lakers -2.5 and -3.5.
The total has dropped from 233.5 to 231.5.

POR vs LAL Key Injuries and Notes

Portland: Front end of a back-to-back, hosting the Spurs on Saturday.
Portland: Four players scored 20 or more points in the last meeting.
Los Angeles: Shot 56.3% and made 17 three-pointers in the first meeting but still lost.
Los Angeles: Luka Doncic and Austin Reaves carry the scoring load.

Trail Blazers vs Lakers ATS and Total Picks

ATS Pick: Trail Blazers +2.5 (-101). Portland has owned this matchup recently and enters on a three-game win-and-cover streak. The Blazers’ depth gives them an advantage over a Lakers team that relies heavily on two stars, and Portland already proved it can win in Los Angeles this season. Bettors who can find +3.5 should grab the extra point.

Moneyline Pick: Portland Trail Blazers. With the spread this short, Portland is a strong value play to win outright based on the matchup history and its balanced scoring.

Total Pick: Over 231.5 (-105). Each of the last four meetings has gone over, averaging 245.3 points per game. The first meeting this season produced 265 points. The total has dropped two points from the opener, giving over bettors a better number in a series that consistently produces high-scoring games.

Trail Blazers vs Lakers Best Bets

Best Bet: Trail Blazers +2.5 (-101)
Moneyline Pick: Portland Trail Blazers
Total Pick: Over 231.5 (-105)
Key Factor: Portland’s scoring depth against a Lakers team reliant on Doncic and Reaves
X-Factor: Whether Portland looks ahead to Saturday’s game against the Spurs

Final Score Prediction for Trail Blazers vs Lakers

Expect another high-scoring battle in this series, with Doncic and Reaves doing everything they can for Los Angeles. Portland’s balanced attack should prove too much again, as the Blazers complete their road trip with a fourth straight win and send this game over the total.