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Best Home Run Prop Bets Today – HR Prop Picks For Tuesday, July 22

Jose Altuve looks to pass home run prop picks - July 22, 2025

The 2025 MLB season is here, and who doesn’t love home run prop bets? Tons of home runs were hit last season and we’re ready to pick more winners in 2025! Free home run prop picks each day come at you compliments of WagerTalk.

We cashed AGAIN with William Contreras at +330 to hit a home run on Monday so let’s see if we can beat the books with home run prop bets on Tuesday! You can find free MLB picks every day at WagerTalk! Here are the best home run prop bets to make for Tuesday, July 22!

Best Home Run Prop Bets – MLB Free HR Props Picks

James Wood (WSH) +400

All-star James Wood had his first multi-hit game since July 3rd yesterday and we think he has a solid chance to build on that success as the Nationals host the Reds once again tonight.

Cincinnati sends rookie Chase Burns to the mound who has allowed three home runs in 16 innings pitched on the season and sporting a 10.80 road ERA.

Two of his three home runs given up have been to lefties while allowing lefties in general to bat .323 on the season to go along with a .548 slugging percentage.

At home Wood is batting .276 while posting a .546 slugging percentage and although he’s been cold as of late he’s 8-16 with four doubles against the Reds this season.

Although Wood has been cold in general as of late, he still has 24 home runs this season and is batting .321 while slugging .638 in night games.

Take Wood at +400 to hit a home run tonight with other Nationals hitters who could potentially hit a home run include Josh Bell and C.J. Abrams (+560)

MLB HR Props Best Bet of the Day #2: Jose Altuve (HOU) +560

Eduardo Rodriguez has struggled mightily across his last two starts combining to pitch 8.1 innings while allowing 12 earned runs including five home runs.

We think he’s vulnerable to give up another home run or two tonight leading us to take Jose Altuve to hit his 18th home run of the season.

The Astros second baseman has been on fire in July batting .365 and slugging .698. He hasn’t been great against lefties in general this season, but that’s not normal for Altuve who hit .370 while slugging .539 against lefties in 2024.

Altuve and Rodriguez have crossed paths quite a bit over their career’s with Altuve going 9-27 with two home runs in his career against the Arizona starter.

Not only has Rodriguez been struggling as of late but at home he’s been mediocre at best this season posting a 6.32 ERA while allowing eight home runs in 37 innings pitched.

With Rodriguez looking shaky heading in, take Altuve to hit a home run tonight at +560 with other Astros batters to take advantage of for a home run include Christian Walker (+450) and Yanier Diaz (+600).

Tuesday MLB Predictions Today | MLB Top Picks Today for July 22, 2025 | Drew’s Daily Diamond

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