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Angels vs Guardians Prediction and Betting Odds April 27

Mike Trout of Angels slides into home plate for a NRFI

Angels vs Guardians Betting Preview and Odds

Guardians starting pitcher Zach Plesac and his 1.53 ERA takes the mound tonight trying to put an end to their 5-game losing streak. WagerTalk MLB Analyst Brian Ochsner offers his Los Angeles Angels vs Cleveland Guardians betting preview for Wednesday, April 27, with the first pitch scheduled for 9:38pm ET / 6:38pm PT.

Stay on top of the latest MLB news and betting notes from Vegas!

Wednesday, April 27 MLB Betting Notes, Courtesy of Caesars
Moneyline: Los Angeles Angels -198 vs Cleveland Guardians +178
Runline: Angels -1.5 (+115) / Guardians +1.5 (-135)
Total: 7.5 Runs (Over -110 / Under -110)
Game Time: 9:38pm ET / 6:38pm PT
Where: Angel Stadium in Anaheim, CA
Weather: 60 Degrees / Clear

Angels vs Guardians Analysis

The Cleveland Guardians visit southern California to play the Los Angeles Angels for the third in a four-game set. Zach Plesac will face Shohei Ohtani in hopes that the Guardians can get off the schneid, after losing the first two games 3-0 and 4-1.

Guardians Getting Worse

Cleveland seems to have lost its hitting mojo in the Bronx versus the Yankees, and haven’t found it against the Halos. They’ve scored just eight runs in their last five games on the road. In Tuesday night’s game, they had four hits, one run, one walk and a whopping 12 strikeouts.

The Guardians started the year hitting well, as they were one of the top 10 teams in baseball in OPS. Now they’ve slid back to the pack with a 13th-best OPS of .707 and a respectable team batting average of .250.

On the bright side, right-handed starter Zach Plesac has put up good numbers in 2022. In three starts and 17.1 innings of work, he’s compiled a 1.53 ERA and 1.08 WHIP, allowed 17 hits, two walks and struck out 10. Plesac will need to have a strong outing Wednesday night to give the Guardians a chance to win.

It’s Sho-Time!

The Angels lineup is starting to find their groove. Anthony Rendon went 2-for-4 with a run scored Tuesday night, Mike Trout powered the Halos attack with two hits (including one home run), three RBI, a walk and a run scored.

The one through seven hitters in this lineup are pretty solid and if the pitching holds up, gives this Angels team a good chance to compete for the playoffs.

Starter Patrick Sandoval had an excellent seven innings of work, giving up just two hits, one walk and striking out nine.

Tonight’s starter, Shohei Ohtani has had two good outings against Houston sandwiched with a forgettable start versus Texas.

While his ERA is bloated at 4.40, the rest of his numbers are pret-ty, pret-ty good as Larry David would say. In 14.1 innings he has 26 strikeouts, a 1.15 WHIP, and allowed just 11 hits and four walks. I like Ohtani’s chances against a strikeout-prone Cleveland team.

Angels vs Guardians Prediction

After a shaky weekend series against the Orioles, the Angels have put together two solid performances in this series. And while Cleveland’s pitching has been decent, the offense has been missing in action.

The Guardians have lost five in a row, while the Angels have a three-game winning streak. As they say in financial markets, you don’t want to try to catch the proverbial “falling knife,” which right now in baseball is the Cleveland Guardians. That’s why I’ll take the Angels on the run line.

Prediction: Los Angeles Angels -1.5 run line

Caesars Sports Book Logo

Interested in placing a bet on Wednesday’s Angels vs Guardians American League clash? Caesars Sports is offering up to a $1,500 match bet for first-time deposits in New Jersey, West Virginia, Colorado, Indiana, Iowa, Michigan, Virginia, Tennessee, Arizona, New York and Louisiana.

First Pitch | MLB Betting Preview for April 27

Join Drew Martin and a rotating panel of guests for First Pitch as we break down the daily baseball slate from a betting perspective. Marlins starting pitcher Pablo Lopez takes his MLB best 0.52 ERA into Nationals Park for his start against Washington tonight. Join WagerTalk’s team of MLB betting experts every weekday at 1:45pm ET / 10:45am PT for First Pitch as we discuss the baseball betting slate.

MLB Picks, Predictions and Odds |  First Pitch Daily Baseball Betting Preview | April 27

WagerTalk Live Odds Screen

WagerTalkโ€™s Live Odds Screen features up-to-the-minute lines from a variety of offshore and domestic sports books. Track the MLB moneylines, run lines and betting percentages for all of Wednesday’s baseball games, including this Angels vs Guardians showdown, from your desktop or phone.

MLB Odds April 27

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Meet the Author

Brian Ochsner graduated from Kansas State University with degrees in Accounting and Agribusiness. He’s a life-long baseball fan and “numbers guy” who tolerates the Colorado Rockies (bad ownership), and is a Denver Broncos and Kansas State Wildcats fan. Along with his interest in the sports wagering industry, he enjoys eating good BBQ, reading books on marketing, finance and economics, and playing Texas Hold ‘Em poker.

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