Washington vs Purdue Prediction, Picks & Odds

A preseason Top 25 ranking, a reported $4 million quarterback and a head coach who took back play-calling duties. Six weeks later, Washington has lost three straight games for the first time since 2021, its starting quarterback is out with a rib injury and its running game ranks 135th in the country.

Meanwhile, Purdue is riding its first Big Ten win streak since 2022. Our Washington vs Purdue prediction breaks down why the Boilermakers are positioned to keep rolling, how the spread climbed through the key number of 3 and where the value sits on the spread, moneyline and total. For more college football picks, check out the rest of our weekly card.

Washington vs Purdue Quick Picks and Prediction

Spread Pick: Purdue -3.5 (-108)
Total Pick: Under 51.5 (-105)
Projected Final Score: Purdue 31, Washington 17

Odds and Line Movement for Washington vs Purdue

Purdue sat at -3 for most of the first two days before the market pushed the Boilermakers through the key number to -3.5, even touching -4 briefly. The total has bounced between 51.5 and 52.5 since opening. Follow every move through kickoff on our live odds page.

Opening Odds

Team	Spread	Total
Washington	+3 (-115)	Over 51.5 (-110)
Purdue	-3 (-105)	Under 51.5 (-110)

Current Odds

Team	Spread	Total
Washington	+3.5 (-112)	Over 51.5 (-115)
Purdue	-3.5 (-108)	Under 51.5 (-105)

Line Movement – Spread

Date	Washington	Purdue
10/12	+3.5 (-112)	-3.5 (-108)
10/12	+4 (-118)	-4 (-102)
10/12	+3.5 (-112)	-3.5 (-108)
10/12	+3.5 (-120)	-3.5 (+100)
10/12	+3 (-105)	-3 (-115)
10/12	+3 (-108)	-3 (-112)
10/11	+3 (-105)	-3 (-115)
10/11	+3 (-108)	-3 (-112)
10/11	+3 (-112)	-3 (-108)
10/11	+3 (-108)	-3 (-112)
10/11	+3 (-110)	-3 (-110)
10/11	+3 (-112)	-3 (-108)
10/11	+3 (-115)	-3 (-105)

Purdue -3 had its price adjusted repeatedly before the market finally moved off the key number. The Boilermakers are now drawing 93 percent of the spread money, while the tickets are split evenly with Washington holding 50 percent.

Line Movement – Total

Date	Over	Under
10/13	51.5 (-115)	51.5 (-105)
10/13	52.5 (-105)	52.5 (-115)
10/13	51.5 (-115)	51.5 (-105)
10/13	52.5 (-105)	52.5 (-115)
10/13	51.5 (-115)	51.5 (-105)
10/13	52.5 (-102)	52.5 (-118)
10/12	52.5 (-105)	52.5 (-115)
10/11	52.5 (-110)	52.5 (-110)
10/11	52.5 (-105)	52.5 (-115)
10/11	51.5 (-110)	51.5 (-110)

The total has toggled between 51.5 and 52.5, returning to its opening number of 51.5. The betting split leans hard in opposite directions, with 97 percent of the money on the under and 67 percent of the tickets on the over.

Washington vs Purdue Key Matchups and Handicap

Washington’s Quarterback Controversy

Few teams have fallen as fast as Washington. The Huskies entered the season with a Top 25 ranking in the preseason polls, but they have now dropped three straight games for the first time since Jimmy Lake’s tenure in 2021. Many of the early-season concerns about Jedd Fisch’s team have come home to roost.

The biggest storyline surrounds quarterback Demond Williams. There have been reports of a disconnect between Williams and his teammates, stemming from his flirtation with LSU in the transfer portal before he returned to Seattle, as well as the unconditional embrace he received from Fisch last winter. Williams has hardly looked worth his reported $4 million price tag, and he was knocked out of last week’s game against Iowa with a rib injury.

Former Stanford quarterback Elihjah Brown took over and got the offense moving in the second half, but it came too late in a dominant 41-24 win for Iowa and Kirk Ferentz. Williams is expected to miss this week, which sets up Brown to start. Anyone ready to endorse Brown based on that performance should remember that Iowa was playing loose defensively while protecting a huge lead.

The problems extend beyond the quarterback position. Washington is not running the ball effectively, averaging just 90 rushing yards per game, which ranks 135th nationally alongside programs such as Northern Illinois and Delaware. There is also growing suspicion that Fisch may be regretting his decision to take back play-calling duties this season.

Purdue’s Ground Game vs a Leaky Run Defense

Washington’s defense has its own issues. Iowa running back Kamari Moulton sliced through the Huskies for 208 rushing yards last week, and that film should excite Purdue’s top rusher, Fame Igeboi. The Minnesota transfer is on pace for a 1,000-yard season and has a favorable matchup against a front that just got gashed on the ground.

Quarterback Ryan Browne gives Purdue a reliable complement to the run game. Browne has been remarkably efficient, completing 69 percent of his passes with nine touchdown passes and only one interception. That combination of a productive back and a mistake-free quarterback is exactly what a struggling Washington defense does not want to see.

Boilermakers Riding a Big Ten Win Streak

Purdue is on its first Big Ten winning streak since 2022, the final season of Jeff Brohm’s tenure, after last week’s blowout of Minnesota. Head coach Barry Odom has his team believing it can aim high, whether that means channeling famous alum Neil Armstrong and shooting for the moon or simply landing the program’s first bowl bid in four years. Washington’s slide is music to Purdue’s ears, and the Boilermakers arrive with momentum on their side.

WASH vs PUR Betting Trends

Washington has lost three straight games for the first time since 2021.
Purdue is on its first Big Ten win streak since 2022.
Washington ranks 135th in the country in rushing at 90 yards per game.
Washington allowed 208 rushing yards to Iowa’s Kamari Moulton in last week’s 41-24 loss.
Purdue is drawing 93 percent of the spread money, while the spread tickets are split 50-50.
The spread has moved from Purdue -3 to -3.5, briefly reaching -4.
The total returned to its 51.5 opener, with 97 percent of the money on the under and 67 percent of the tickets on the over.

WASH vs PUR Key Injuries and Notes

Washington quarterback Demond Williams suffered a rib injury against Iowa and is expected to miss this game.
Former Stanford quarterback Elihjah Brown is in line to start for Washington after leading second-half production against Iowa.
Jedd Fisch took back play-calling duties for Washington this season.
Purdue running back Fame Igeboi is on pace for a 1,000-yard rushing season.
Purdue quarterback Ryan Browne has completed 69 percent of his passes with nine touchdowns and one interception.
Purdue is chasing its first bowl bid in four years.
Check final injury reports before kickoff for any changes to Washington’s quarterback situation.

Washington vs Purdue ATS and Total Picks

Purdue -3.5 Spread Pick

Purdue holds the edge in nearly every key area. The Boilermakers have an efficient quarterback, a 1,000-yard pace running back and the confidence of a Big Ten win streak. Washington is starting a backup quarterback, cannot run the ball and just allowed more than 200 rushing yards to a single back. The market has noticed, with 93 percent of the money pushing Purdue through the key number of 3. Even at -3.5, the Boilermakers are the right side.

Pick: Purdue -3.5 (-108)

WASH vs PUR Under Pick

Washington’s offense is in a difficult spot. A backup quarterback, a running game ranked 135th nationally and questions surrounding the play-calling all limit how many points the Huskies can produce. Purdue’s formula of running the ball with Igeboi and taking efficient shots with Browne also tends to keep the clock moving. With 97 percent of the money on the under, this total looks a little too high for a game where one offense is likely to sputter.

Pick: Under 51.5 (-105)

Washington vs Purdue Best Bets

Best Bet: Purdue -3.5 (-108)
Total: Under 51.5 (-105)

Purdue on the spread is the top play. The Boilermakers have momentum, a strong rushing matchup and a reliable quarterback, while Washington is dealing with a quarterback controversy, a non-existent ground game and a three-game skid. Purdue on the moneyline offers a straightforward way to back the better team, and the under pairs naturally with a Huskies offense that should struggle to keep pace.

Final Score Prediction for Washington vs Purdue

Purdue leans on Fame Igeboi to attack a Washington run defense that was just gashed by Iowa, while Ryan Browne avoids mistakes and keeps drives alive. Elihjah Brown has moments for the Huskies, but without a running game to support him, Washington cannot sustain enough offense to keep up. The Boilermakers extend their Big Ten win streak and take another step toward a bowl bid.