Mississippi State vs Iowa State Predictions, Picks, Odds, and Trends

Mississippi State vs Iowa State Prediction: Mississippi State got an early scare against North Alabama last week, and that might not necessarily be a bad thing as the Bulldogs prepare for this non-conference showdown.

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Quick Picks and Prediction on Mississippi State vs Iowa State

If you’re in a hurry, here’s a quick summary of what to expect:

Mississippi State survived an early-season scare, which could sharpen them for this neutral-site clash.
Iowa State has yet to face a high-caliber opponent this season.
Mississippi State’s veteran guard Josh Hubbard gives them an edge in backcourt experience.
Expect a competitive game, but the Bulldogs have legitimate upset potential in Sioux Falls.
Prediction: Mississippi State +3 (upset alert).

Mississippi State vs Iowa State Odds and Line Movement

Check out the college basketball odds page for the opening and live odds for this matchup, along with line movement updates from the sportsbook consensus.

Opening Odds for Mississippi State vs Iowa State

Team	Spread	Moneyline	Total
Mississippi State	+4.5	+165	150.5
Iowa State	-4.5	-200	150.5

Live Current Odds for Mississippi State vs Iowa State

Team	Spread	Moneyline	Total
Mississippi State	+5.5	+195	150.5
Iowa State	-5.5	-230	150.5

Key Matchups for Mississippi State vs Iowa State

Mississippi State’s close call against North Alabama may serve as a wake-up call ahead of this neutral-site battle.

A similar pattern unfolded last season when the Bulldogs struggled early against Southeastern Louisiana before finding rhythm in wins over Utah, SMU, and UNLV. The test will be tougher here, but the Bulldogs’ battle-tested nature bodes well.

Iowa State enters this game largely untested, coasting past Fairleigh Dickinson and Grambling in its first two outings.

The Cyclones feature a strong frontcourt with scoring depth but must replace two All-Big XII guards — Curtis Jones and Keshon Gilbert — which leaves questions in their backcourt cohesion.

Meanwhile, Mississippi State’s Josh Hubbard, who has started 51 consecutive games, offers veteran stability and perimeter confidence that could expose Iowa State’s transitional guard play. Expect this matchup to hinge on tempo control and three-point efficiency.

Opponents took 47.8% of their total field goal attempts from beyond the arc, a strategy built on forcing low-percentage perimeter shots and eliminating easy looks near the rim.

Betting Trends for Mississippi State vs Iowa State

Mississippi State is 4-1 ATS in its last five neutral-site games.
The Bulldogs are 5-2 ATS following a non-conference win.
Iowa State is 1-4 ATS in its last five games vs SEC opponents.
The Under has hit in 7 of Iowa State’s last 9 games as a favorite.

Key Injuries and Analysis

Mississippi State: No major injuries reported.
Iowa State: Guard rotation still adjusting after departures of Jones and Gilbert.

This could favor the Bulldogs’ veteran backcourt, especially in late-game execution scenarios.

Mississippi State vs Iowa State ATS and Over/Under Betting Picks

This section summarizes the betting perspective for both the spread and total.

Spread Pick

Mississippi State +5.5 — The Bulldogs’ balance and experience make them live underdogs in Sioux Falls.

Total Pick

Under 137.5 — Expect defense and rebounding to dictate pace early, with both teams taking time to find rhythm.

Mississippi State vs Iowa State Final Score Prediction

Final Score Prediction: Mississippi State 68, Iowa State 65

The Bulldogs’ ability to withstand early pressure and lean on Josh Hubbard’s leadership could be the difference. Iowa State’s interior depth keeps it close, but the guard edge and composure favor Mississippi State to earn a statement non-conference win.

How to Bet on Mississippi State vs Iowa State

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