Best Monday Night Football Player Props For 49ers vs Colts | NFL Week 16
Best Monday Night Football Player Props 49ers vs Colts!
Sportsmemo’s Steve Seagrave provides the best Week 16 Monday Night Football player props tonight for 49ers vs Colts before kickoff! His articles offer up-to-the-minute lines, NFL moneylines, run lines, and betting percentages.
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Best NFL Monday Night Football Player Props Prediction: George Kittle, 49ers Anytime Touchdown (+125)
George Kittle is in a groove as he’s registered 67+ receiving yards in five straight games while scoring a touchdown in three of those contests.
Kittle is coming off a game against the Tennessee Titans where he caught 8/9 passes for a season high 88 receiving yards.
A big part of the recent success is Brock Purdy being fully healthy as the two players have great chemistry and Kittle has scored in 9 of his last 17 starts.
Now Kittle will have an opportunity to feast on an Indianapolis Colts defense that has allowed the 5th most receiving yards to opposing tight ends with 66+ yards per game.
Wide receiver Ricky Pearsall has already been ruled out for this game which give San Francisco one less weapon to work with.
Kittle has been targeted in the red zone in 4 of Purdy’s 5 starts and I’m banking on the 49ers utilizing him to expose the Colts vulnerabilities against the tight end position.
Best NFL Monday Night Football Player Props Prediction: Philip Rivers, Colts OVER 17.5 Pass Completions (-130)
You have to root for Phillip Rivers in his return, but it was obvious that his arm strength isn’t there as he averaged only 4.7 air yards per target with his longest completion going for only 17 yards.
Rivers did complete 18 of his 27 passes and I fully expect the Indianapolis Colts to continue to utilize the short passing game.
The San Francisco 49ers have been a passing funnel in 2025 as they have allowed the 6th most completions with an average of 23.6 per game.
We have seen 10/14 opposing quarterbacks eclipse their respective completions line against the 49ers (+3.07 avg/game) and 11 of those 14 have beat this exact line. In fact, the only quarterbacks to fall short were Shedeur Sanders (16), Baker Mayfield (17) and Sam Darnold (16).
Rivers will be playing behind one of the best offensive lines in the NFL in perfect conditions at home in Indianapolis. He should also see a pass heavy game script as the Colts enter this game -5.5-point underdogs.
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