2025 NFL Off Season Updates Presented by GoldSheet | Arizona Cardinals
Arizona Cardinals quarterback Kyler Murray has started every game since returning from a torn ACL in November 2023. As one of the smallest quarterbacks in the NFL at 5-foot-10, how long will Murray be able to continue that impressive streak?
2025 Arizona Cardinals Team Preview
NFC West Odds
| Team | SB LX Odds | NFC | Division | Win Total |
| 49ers | +2000 | +1000 | +145 | 10.5 (o +110 / u -130) |
| Rams | +2200 | +1100 | +200 | 9.5 (o -145 / u +120) |
| Seahawks | +7500 | +3500 | +475 | 8.5 (o +115 / u -140) |
| Cardinals | +7500 | +3500 | +475 | 8.5 (o EV / u -120) |
Odds above courtesy of DraftKings as of May 22. The Arizona Cardinals went 8-9 straight-up, 11-6 against the spread last season while finishing third in the NFC West.
Arizona Cardinals Roster Moves
QBs on Roster: Kyler Murray (7th Year); Jacoby Brissett (1st Year w/ Team); and Clayton Tune (3rd Year)
Coaching Changes: No major changes. Head coach Jonathan Gannon, offensive coordinator Drew Petzing and defensive coordinator Nick Rallis will all return.
Key Acquisitions: Defensive end Josh Sweat; Linebacker Akeem Davis-Gaither; Defensive lineman Calais Campbell; and reserve quarterback Jacoby Brissett
Key Departures: Defensive lineman Roy Lopez; Center Trystan Colon; Defensive end Dennis Gardeck; Kicker Matt Prater; Offensive lineman Will Hernandez; and linebacker Kyzir White
2025 Arizona Cardinals Draft Picks: R1 P16 Walter Nolen, DL, Ole Miss; R2 P47 Will Johnson, CB, Michigan; R3 P78 Jordan Burch, DL, Oregon; R4 P115 Cody Simon, LB, Ohio State; R5 P174 Denzel Burke, CB, Ohio State; R6 P211 Hayden Conner, IOL, Texas; and R7 P225 Kitan Crawford, S, Nevada
2025 Arizona Cardinals Schedule
****GS Line represents our projected point spreads using our summer power ratings. Special thanks to Ralph Michaels (@CalSportsLV) for his assistance in putting the schedules together with rest disparities and DraftKings’ opening spreads.
2025 NFL Dates to Remember
- Mid-July – Training camps open
- July 31 – Hall of Fame Game in Canton, Ohio (Chargers vs Lions)
- September 4 – The Philadelphia Eagles will host the first regular season game (vs Cowboys).
- September 5 – The Los Angeles Chargers will serve as the host for the second game in São Paulo, Brazil against the Kansas City Chiefs.
- February 9 – Super Bowl LX at Levi’s Stadium in Santa Clara, California.
2025 Football GoldSheet Early Bird Special
Subscribe to the country’s longest-running sports betting newsletter for less than $7 per week. The Football GoldSheet will be your betting concierge through the 2025-26 football season, offering weekly NFL and NCAAF game previews, stat logs and much more. Early-bird subscribers will begin receiving preseason content in May as we recap the NFL draft and schedule release, plus season win totals and division previews.
WagerTalk Live Odds Screen
WagerTalk’s live odds screen features up-to-the-minute lines from a variety of offshore and domestic sports books. Track the moneylines, point spreads, totals and betting percentages for all of the Arizona Cardinals games from their release in May all the way through Week 1 in September. Find free NFL picks from season win total bets through Super Bowl futures on our free picks pages.
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