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Chicago White Sox vs Cleveland Guardians Prediction and Betting Odds July 22

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Chicago White Sox vs Cleveland Guardians Betting Preview

WagerTalk MLB handicapper Andy Lang offers his analysis of Friday night’s Chicago White Sox vs Cleveland Guardians Prediction and Betting Odds July 22 clash at Guaranteed Rate Field. Both the White Sox and Guardians sit within three games of first place in the AL Central.

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Friday, July 22 MLB Betting Notes, Courtesy of Caesars
Moneyline: Chicago White Sox -145 vs Cleveland Guardians +122
Runline: White Sox -1.5 (+140) / Guardians +1.5 (-160)
Total: 8.5 Runs (Over -105 / Under -115)
Game Time: 8:10pm ET / 5:10pm PT
Where: Guaranteed Rate Field in Chicago, IL
Weather: 85 Degrees / Clear

Chicago White Sox vs Cleveland Guardians Analysis

Major League Baseball is back in action Friday night as the Chicago White Sox host Cleveland Guardians in the first game of a four game set from Guaranteed Rate Field.

This is a critical series as the resurgent White Sox evened out their record at 46-46 look to gain ground on the 46-44 Guardians. Both teams sit only two and three games behind the MinnesotaTwins respectively.

Cal Quantrill gets the start for Cleveland, while Lucas Giolito toes the rubber for Chicago, they are both righties with 6-5 records who are separated by less than a year age-wise. First pitch is scheduled for 8:10 PM EST/5:10 PST.

White Sox Making Their Move

The Chicago White Sox entered this season as the favorite to win the American League Central but they got off to a slow start mostly due to injuries.

They began heating up before the break, winning 11 of 18 and 5 of their last 6 games. They enter this contest at 46-46 in third place, only three games behind the Minnesota Twins.

The Pale Hose are a mixed bag offensively, 15th in runs scored, 3rd in batting average, 24th in home runs and 18th in slugging percentage.

Lucas Giolito gets the nod for Chicago, he is 6-5 on the season with a 4.69 ERA in 16 starts. Giolito has owned the Guardians with a 2-0 record, 0.68 ERA and 10 strikeouts in two outings against them.

Guarding Their Ground

The Cleveland Guardians ended the first half winning five of their last seven games, resulting in a 46-44 record. They ended on a high note with a sweep of the Detroit Tigers.

They now sit a game ahead of the Chicago White Sox and two games behind the MinnesotaTwins in the division. The Guardians rank similar to the Pale Hose in statistically at 16th in runs scored, 9th in batting average, 28th in home runs and 19th in slugging percentage.

Cal Quantrill gets the start for Cleveland on Friday night to open the second half. Quantrill is 6-5 on the season with a 3.75 ERA in 15 outings. He blanked the Detroit Tigers for six innings in his last start while only allowing four hits and two walks.

However he has struggled with the White Sox, he is 1-1 with a 5.84 ERA and only six strikeouts across two starts.

Andy Lang MLB Picks

Chicago White Sox vs Cleveland Guardians Prediction

The Chicago White enter this contest as -150 money line favorites, while the Cleveland Guardians sit at +135 with a total of 8.5. Both these teams ended the first half on hot streaks and both have similar records and offensive units.

Both starters rank closely statistically on the season as well, however Giolito has been filthy against the Guardians throughout his career. He sports a 5-3 record with a 1.77 ERA and 81 strikeouts across 12 appearances.

The Guardians do have a slightly better bullpen, but I favor the Pale Hose bats as they aren’t as reliant on one individual player like Jose Ramirez. Let’s just keep the bullpens out of it and take the Chicago White Sox -0.5 in the first five at -115 odds.

Prediction: Chicago White Sox -0.5 F5 -115 DK (first five innings)

Caesars Sports Book Logo

Interested in placing a bet on Friday’s Chicago White Sox vs Cleveland Guardians AL Central clash? Caesars Sports is offering up to a $1,500 match bet for first-time deposits in New Jersey, West Virginia, Colorado, Indiana, Iowa, Michigan, Virginia, Tennessee, Arizona, New York and Louisiana.

First Pitch | MLB Predictions for Friday, July 22

Join Drew Martin and a rotating panel of guests for First Pitch as we break down the daily baseball slate from a betting perspective. Join WagerTalk’s team of MLB betting experts every weekday at 1:45pm ET / 10:45am PT for First Pitch as we discuss the baseball betting slate.

MLB Picks, Predictions and Odds |  First Pitch Daily Baseball Betting Preview | July 22

WagerTalk Live Odds Screen

WagerTalk’s Live Odds Screen features up-to-the-minute lines from a variety of offshore and domestic sports books. Track the MLB moneylines, run lines and betting percentages for all of Friday’s baseball games, including this Chicago White Sox vs Cleveland Guardians showdown, from your desktop or phone.

MLB Odds July 22

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Meet the Author

Andy Lang has lived in Indianapolis his whole life, and like most people from the Hoosier State, he became fascinated with motor sports. That interest in motor sports turned into a desire to make money off the sport through fantasy contests and sports betting. Like most, he took his lumps when he first got started, but now he is one of the most respected NASCAR bettors in the industry. Andy has expanded that sports betting experience to become profitable in a number of other sports, transforming this interest from a side hobby to a major source of income.

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