Astros vs Phillies Prediction and Betting Preview | June 25

Wednesday’s Astros vs Phillies clash in Houston will be Zack Wheeler’s first road start in over a month. Philadelphia’s ace has been good regardless of the location this season, but this trip to Texas could present some obstacles. The GoldSheet team offers its thoughts on tonight’s interleague clash at Daikin Park.
Astros vs Phillies Betting Preview
Time | 8:10pm ET / 5:10pm PT |
Stadium | Daikin Park in Houston |
Weather | Dome |
MoneyLine | Philadelphia -155 / Houston +135 |
Total | 7.5 Runs (o -105 / u -115) |
RunLine | Philadelphia -1.5 (+110) / Houston +1.5 (-135) |
Philadelphia Phillies
The Mets’ recent slide has allowed the Phillies to take a 1.5-game lead in the NL East entering Wednesday. Philadelphia’s bats were alive against the Mets over the weekend, but outside of that series, the Phillies’ offense has been sputtering a bit. Since Memorial Day, the Phillies are hitting .247 (No. 14 in MLB) with a 98 wRC+ (No. 16) while scoring an average of 4.19 runs per game (No. 20).
Philadelphia’s lineup has not been great against left-hand pitching this season, particularly in the month of June with Bryce Harper missing some time. The Phillies are hitting .238 against lefties (No. 18 in MLB) with a .314 on-base percentage (No. 15) and a 87 wRC+ (No. 22) in June.
Wheeler has been fantastic for the Phillies this season, but the Astros’ lineup has enjoyed a small level of success against him. Houston’s current lineup is hitting .270 in 79 plate appearances against Wheeler with eight extra-base hits.
Houston Astros
Unlike Wheeler’s matchup against the Astros’ lineup, Houston’s Colton Gordon will have the element of unfamiliarity on his side. This will be Philadelphia’s first time seeing the Astros’ rookie.
Gordon has settled into his role nicely over the last few weeks. In his last three starts, he has a 2.81 ERA with 14 strikeouts compared to just two walks.

Astros vs Phillies Prediction
Houston is 18-8 in home games against right-hand starting pitchers this season, while Philadelphia is 3-5 against lefties on the road. The Astros have won each of their last seven as a home ‘dog.
HOUSTON ASTROS +135 ML
Daily MLB Stat Sheet
GoldSheet’s daily MLB stat sheet provides marquee hitter vs pitcher matchup notes, one traditional free play, one prop play, batting stats in a variety of categories and Ralph Michaels’ first inning trends sheet each morning around 9am ET / 6am PT. Oh yeah, we forgot to mention the price…FREE! Download your copy and check out what’s inside.

WagerTalk Live Odds Screen
WagerTalk’s live odds screen features up-to-the-minute lines from a variety of offshore and domestic sports books. Track the moneylines, runlines, totals and betting percentages for every MLB game this summer, including tonight’s Astros vs Phillies contest. Find free MLB picks every day through out the season on our free picks pages.
**************************************************
Looking for more free sports picks and sports betting tips? Go beyond the anytime touchdown scorer picks!
- Latest Betting Odds and Public Action: Vegas lines updated in real time, including who the public is betting on and anytime touchdown scorer odds.
- Last Minute Handicapping Advice: Check out our extensive library of handicapping tips and advice from professional Vegas handicappers (we also recommend taking the time to look over our sports betting tips video library)
- Want an expert opinion? Check out the latest Free Sports Picks and Best Bets from our team of expert sports handicappers.
Make sure to bookmark all the above!