Detroit Pistons vs New York Knicks Odds, Picks and Prediction For October 27, 2026

One team is perfect, the other is still looking for its first win, and yet the winless team is laying points. That’s the puzzle at the center of this Pistons vs Knicks prediction. Detroit travels to Madison Square Garden on October 27, 2026, at 8:00 PM ET carrying a 3-0 record, while New York sits at 0-3 and has struggled to score in every game.

The market still trusts the Knicks at home, but the Pistons have been the more efficient team on both ends of the floor. Injuries to Detroit’s frontcourt add a wrinkle, so before you finalize your NBA picks, here’s a complete breakdown of the odds, line movement, matchups, and best bets for Pistons vs Knicks.

Pistons vs Knicks Quick Picks and Prediction

Spread Pick: Detroit Pistons +3.5 (-112)
Total Pick: Under 219.5 (-112)
Projected Final Score: Pistons 106, Knicks 105

Odds and Line Movement for Detroit vs New York

The spread opened at New York -3.5, briefly climbed to 4.5, and has since settled back at 3.5. The total moved in the opposite direction, rising a point from 218.5 to 219.5. Track every adjustment with our live odds.

Opening Odds

Team	Spread	Total
Detroit Pistons	+3.5 (-105)	Over 218.5 (-115)
New York Knicks	-3.5 (-115)	Under 218.5 (-105)

Current Odds

Team	Spread	Total
Detroit Pistons	+3.5 (-112)	Over 219.5 (-108)
New York Knicks	-3.5 (-108)	Under 219.5 (-112)

Line Movement – Spread

Date	Detroit	New York
10/27	+3.5 (-112)	-3.5 (-108)
10/27	+4.5 (-115)	-4.5 (-105)
10/27	+3.5 (-108)	-3.5 (-112)
10/27	+4.5 (-115)	-4.5 (-105)
10/27	+4.5 (-112)	-4.5 (-108)
10/26	+3.5 (-115)	-3.5 (-105)
10/26	+3.5 (-110)	-3.5 (-110)
10/26	+3.5 (-105)	-3.5 (-115)

Line Movement – Total

Date	Over	Under
10/27	219.5 (-108)	219.5 (-112)
10/26	218.5 (-115)	218.5 (-105)
10/26	219.5 (-105)	219.5 (-115)
10/26	218.5 (-115)	218.5 (-105)

Key Matchups and Handicap: Pistons vs Knicks

This Eastern Conference showdown features two teams heading in opposite directions to begin the 2026-27 NBA season. Detroit is a perfect 3-0 after victories over Boston, Miami, and Philadelphia. New York is 0-3 following losses to Philadelphia, Boston, and Orlando. Despite those contrasting starts, the Knicks are 3.5-point home favorites at Madison Square Garden.

Detroit has been impressive offensively, averaging 118.3 points per game while shooting 47 percent from the field and pulling down 52 rebounds per contest. Cade Cunningham has driven that production with 21.3 points and 8.0 assists per game, giving the Pistons consistent scoring and playmaking every night. The defense has been just as sharp, allowing only 105.7 points per game and holding opponents to roughly 41 percent shooting.

The concern for Detroit is health. Starting center Jalen Duren is sidelined with a hamstring injury, which removes a key interior presence and puts more rebounding responsibility on Paul Reed, who averages 8.3 boards per game.

Ausar Thompson is dealing with an ankle injury, and Isaiah Joe is questionable with a hip issue. If Thompson can’t go, Detroit’s perimeter defense and rebounding depth take another hit.

New York’s problems have been on the offensive end. The Knicks are averaging just 101.7 points per game while shooting 41 percent from the floor. Jalen Brunson leads the way with 22.7 points per game, and Karl-Anthony Towns gives New York a significant edge inside with 12.0 rebounds per contest. With Duren out, Towns could find opportunities to exploit Detroit’s thinned-out frontcourt.

Defensively, the Knicks have stayed competitive, allowing 108.0 points per game, but their offensive inefficiency has been the main reason for three straight losses. New York will also be without guard Jose Alvarado due to an ankle injury, which cuts into its backcourt depth.

The handicap comes down to efficiency versus situation. New York has home-court advantage and a tough interior matchup in Towns, but Cunningham’s ability to control the offense gives Detroit a chance to dictate tempo.

The Pistons’ superior offensive efficiency, rebounding, and defensive consistency make them an attractive underdog, even with the injury concerns. With both defenses allowing fewer than 109 points per game and the Knicks struggling to score, a competitive, lower-scoring game looks likely.

Betting Trends: DET vs NYK

The Pistons are 3-0 straight up to start the 2026-27 season.
The Knicks are 0-3 straight up to start the season.
Detroit is averaging 118.3 points per game on 47 percent shooting.
The Pistons are allowing just 105.7 points per game.
Detroit opponents are shooting roughly 41 percent from the field.
New York is averaging only 101.7 points per game on 41 percent shooting.
The Knicks are allowing 108.0 points per game.
Both teams are allowing fewer than 109 points per game.

Key Injuries and Notes: DET vs NYK

Detroit: Jalen Duren (hamstring) is out.
Detroit: Ausar Thompson is dealing with an ankle injury.
Detroit: Isaiah Joe (hip) is questionable.
Detroit: Paul Reed averages 8.3 rebounds per game and will carry more of the load inside with Duren out.
Detroit: Cade Cunningham is averaging 21.3 points and 8.0 assists per game.
New York: Jose Alvarado (ankle) is out.
New York: Jalen Brunson is averaging 22.7 points per game.
New York: Karl-Anthony Towns is averaging 12.0 rebounds per game.

ATS and Total Picks for Pistons vs Knicks

ATS Pick: Detroit has been the better team through the first week, outscoring opponents by a wide margin while New York has failed to find any offensive rhythm. The spread touched 4.5 before falling back to 3.5, and the Pistons still hold value at that number. Cunningham’s control of the offense and Detroit’s defensive consistency should keep this game close throughout, with a real chance at an outright win. Take the Pistons +3.5.

Total Pick: The total has crept up from 218.5 to 219.5, giving under bettors a slightly better number. Both defenses are allowing fewer than 109 points per game, and the Knicks are averaging just 101.7 points while shooting 41 percent. With Detroit’s frontcourt depleted and New York struggling to score, this sets up as a grind. Take the under 219.5.

Detroit vs New York Best Bets

Best Bet: Detroit Pistons +3.5 (-112)
Total: Under 219.5 (-112)

Final Score Prediction for Pistons vs Knicks

Detroit’s efficiency and Cunningham’s playmaking should be enough to outlast a New York offense that has yet to find its footing, in a tight, low-scoring battle at the Garden.