{"id":40635,"date":"2026-10-14T10:57:12","date_gmt":"2026-10-14T14:57:12","guid":{"rendered":"https:\/\/www.wagertalk.com\/news\/?p=40635"},"modified":"2026-10-14T10:57:13","modified_gmt":"2026-10-14T14:57:13","slug":"ohio-state-vs-indiana-prediction-picks-odds-october-17-2026","status":"publish","type":"post","link":"https:\/\/www.wagertalk.com\/news\/college-football\/ohio-state-vs-indiana-prediction-picks-odds-october-17-2026\/","title":{"rendered":"Ohio State vs Indiana Prediction, Picks &amp; Odds | October 17, 2026"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Ohio State won 30 straight games against Indiana, and then the streak ended in last year&#8217;s Big Ten Championship. Since that upset in Indianapolis, the Hoosiers have gone 9-0 with an average margin of victory of 27.2 points, beating Alabama, Oregon, Miami (Fla.) and Nebraska along the way. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ohio State, meanwhile, has gone 5-2 and is leaning almost entirely on one receiver. Jeremiah Smith is a generational talent, but Curt Cignetti has proven to be a generational coach, and this time the Hoosiers get the Buckeyes at home. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Our <strong>Ohio State vs Indiana prediction<\/strong> breaks down the rematch, the busy line movement and our picks on the spread, moneyline and total. For more <a href=\"https:\/\/www.wagertalk.com\/free-sports-picks\/college-football\">free college football picks<\/a>, check out the rest of our weekly card.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Ohio State vs Indiana Quick Picks and Prediction<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Moneyline Pick:<\/strong> Indiana moneyline<\/li>\n\n\n\n<li><strong>Spread Pick:<\/strong> Indiana +3.5 (-112)<\/li>\n\n\n\n<li><strong>Total Pick:<\/strong> Under 51.5 (-120)<\/li>\n\n\n\n<li><strong>Projected Final Score:<\/strong> Indiana 24, Ohio State 20<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Odds and Line Movement for Ohio State vs Indiana<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Ohio State opened as a 4-point road favorite and has bounced between 3 and 3.5 ever since, settling at -3.5. The total has toggled between 50.5 and 51.5 more than a dozen times. Stay on top of every move with our <a href=\"https:\/\/www.wagertalk.com\/odds\">live odds<\/a> page leading up to kickoff.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Opening Odds<\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Team<\/th><th>Spread<\/th><th>Total<\/th><\/tr><\/thead><tbody><tr><td>Ohio State<\/td><td>-4 (-115)<\/td><td>Over 51.5 (-112)<\/td><\/tr><tr><td>Indiana<\/td><td>+4 (-105)<\/td><td>Under 51.5 (-108)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">Current Odds<\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Team<\/th><th>Spread<\/th><th>Total<\/th><\/tr><\/thead><tbody><tr><td>Ohio State<\/td><td>-3.5 (-108)<\/td><td>Over 51.5 (+100)<\/td><\/tr><tr><td>Indiana<\/td><td>+3.5 (-112)<\/td><td>Under 51.5 (-120)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">Line Movement &#8211; Spread<\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Date<\/th><th>Ohio State<\/th><th>Indiana<\/th><\/tr><\/thead><tbody><tr><td>10\/13<\/td><td>-3.5 (-108)<\/td><td>+3.5 (-112)<\/td><\/tr><tr><td>10\/12<\/td><td>-3.5 (-105)<\/td><td>+3.5 (-115)<\/td><\/tr><tr><td>10\/11<\/td><td>-3.5 (-110)<\/td><td>+3.5 (-110)<\/td><\/tr><tr><td>10\/11<\/td><td>-3.5 (-108)<\/td><td>+3.5 (-112)<\/td><\/tr><tr><td>10\/11<\/td><td>-3 (-120)<\/td><td>+3 (+100)<\/td><\/tr><tr><td>10\/11<\/td><td>-3 (-118)<\/td><td>+3 (-102)<\/td><\/tr><tr><td>10\/11<\/td><td>-3 (-115)<\/td><td>+3 (-105)<\/td><\/tr><tr><td>10\/11<\/td><td>-3 (-112)<\/td><td>+3 (-108)<\/td><\/tr><tr><td>10\/11<\/td><td>-3.5 (-102)<\/td><td>+3.5 (-118)<\/td><\/tr><tr><td>10\/11<\/td><td>-3.5 (-105)<\/td><td>+3.5 (-115)<\/td><\/tr><tr><td>10\/11<\/td><td>-3.5 (-102)<\/td><td>+3.5 (-118)<\/td><\/tr><tr><td>10\/11<\/td><td>-3 (-120)<\/td><td>+3 (+100)<\/td><\/tr><tr><td>10\/11<\/td><td>-3 (-118)<\/td><td>+3 (-102)<\/td><\/tr><tr><td>10\/11<\/td><td>-3 (-120)<\/td><td>+3 (+100)<\/td><\/tr><tr><td>10\/11<\/td><td>-3.5 (-105)<\/td><td>+3.5 (-115)<\/td><\/tr><tr><td>10\/11<\/td><td>-4 (-105)<\/td><td>+4 (-115)<\/td><\/tr><tr><td>10\/11<\/td><td>-4 (-110)<\/td><td>+4 (-110)<\/td><\/tr><tr><td>10\/11<\/td><td>-4 (-115)<\/td><td>+4 (-105)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Ohio State has drawn nearly all of the money from the start, and currently holds 99 percent of the money and 80 percent of the tickets. Yet the line has dropped from 4 to 3.5 and repeatedly tested 3. When a favorite gets that much one-sided support without moving up, it suggests respected money is on the home underdog.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Line Movement &#8211; Total<\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Date<\/th><th>Over<\/th><th>Under<\/th><\/tr><\/thead><tbody><tr><td>10\/14<\/td><td>51.5 (+100)<\/td><td>51.5 (-120)<\/td><\/tr><tr><td>10\/14<\/td><td>50.5 (-120)<\/td><td>50.5 (+100)<\/td><\/tr><tr><td>10\/14<\/td><td>51.5 (+100)<\/td><td>51.5 (-120)<\/td><\/tr><tr><td>10\/14<\/td><td>50.5 (-118)<\/td><td>50.5 (-102)<\/td><\/tr><tr><td>10\/13<\/td><td>51.5 (-102)<\/td><td>51.5 (-118)<\/td><\/tr><tr><td>10\/13<\/td><td>50.5 (-118)<\/td><td>50.5 (-102)<\/td><\/tr><tr><td>10\/13<\/td><td>51.5 (+100)<\/td><td>51.5 (-120)<\/td><\/tr><tr><td>10\/12<\/td><td>50.5 (-118)<\/td><td>50.5 (-102)<\/td><\/tr><tr><td>10\/12<\/td><td>51.5 (-105)<\/td><td>51.5 (-115)<\/td><\/tr><tr><td>10\/12<\/td><td>51.5 (-108)<\/td><td>51.5 (-112)<\/td><\/tr><tr><td>10\/12<\/td><td>50.5 (-118)<\/td><td>50.5 (-102)<\/td><\/tr><tr><td>10\/12<\/td><td>50.5 (-115)<\/td><td>50.5 (-105)<\/td><\/tr><tr><td>10\/12<\/td><td>50.5 (-110)<\/td><td>50.5 (-110)<\/td><\/tr><tr><td>10\/12<\/td><td>50.5 (-105)<\/td><td>50.5 (-115)<\/td><\/tr><tr><td>10\/12<\/td><td>50.5 (-112)<\/td><td>50.5 (-108)<\/td><\/tr><tr><td>10\/12<\/td><td>50.5 (-118)<\/td><td>50.5 (-102)<\/td><\/tr><tr><td>10\/12<\/td><td>51.5 (+100)<\/td><td>51.5 (-120)<\/td><\/tr><tr><td>10\/11<\/td><td>51.5 (-110)<\/td><td>51.5 (-110)<\/td><\/tr><tr><td>10\/11<\/td><td>51.5 (-112)<\/td><td>51.5 (-108)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">The total has been tug-of-war between 50.5 and 51.5. The under drew 100 percent of the money early in the week, while the over now holds 83 percent of the money and 80 percent of the tickets. Even so, the under at 51.5 is priced at -120, showing the market still respects the low side at this number.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><a href=\"https:\/\/splashsports.com\/wagertalk\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2026\/10\/WT-25K-graphic-3-1024x576.png\" alt=\"\" class=\"wp-image-40455\" style=\"width:588px;height:auto\" srcset=\"https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2026\/10\/WT-25K-graphic-3-1024x576.png 1024w, https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2026\/10\/WT-25K-graphic-3-300x169.png 300w, https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2026\/10\/WT-25K-graphic-3-768x432.png 768w, https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2026\/10\/WT-25K-graphic-3-1536x864.png 1536w, https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2026\/10\/WT-25K-graphic-3.png 1672w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\">Ohio State vs Indiana Key Matchups and Handicap<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Indiana&#8217;s Dominant Run Since the Big Ten Title Game<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Ohio State&#8217;s 30-game winning streak over Indiana ended in last year&#8217;s Big Ten Championship, when the Hoosiers won as a 3.5-point underdog in Indianapolis. Indiana&#8217;s defense held Ohio State to just 58 rushing yards in that game, though Jeremiah Smith still broke free for eight catches and 144 yards.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Indiana has been nearly untouchable since. The Hoosiers are 9-0 straight up with an average margin of victory of 27.2 points per game, a stretch that includes wins over Alabama, Oregon, Miami (Fla.) and last week&#8217;s victory at Nebraska. This year&#8217;s team appears to be a tick behind last year&#8217;s championship squad, particularly on offense, but home field and a 3.5-point head start with the defending champions help offset those concerns.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Ohio State&#8217;s Search for a Second Receiver<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Ohio State is 5-2 since the loss to Indiana, with defeats to Miami (Fla.) and Texas, and an average point differential of 23.9 points per game over that stretch. There are holes to poke in the Buckeyes&#8217; resume, and the biggest one is the lack of a second reliable target.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In last year&#8217;s meeting, Ohio State had a viable second option in Carnell Tate, who went on to become a top-five draft pick of the Titans. Halfway through this season, the Buckeyes still have not found this year&#8217;s Tate. In the win over Iowa two weeks ago, Smith caught more passes (11) than the rest of the team combined (9). In last week&#8217;s win over Maryland, quarterback Julian Sayin threw only 11 passes that were not targeted toward Smith.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Hoosiers Trust Curt Cignetti&#8217;s Game Plan<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Smith is unquestionably one of the best wide receiver prospects in recent memory, but if there is any coach in the country to trust with a proper game plan, it is Curt Cignetti. When an offense funnels this much of its production through one player, a well-prepared defense can make life difficult. Cignetti&#8217;s staff already held Ohio State to 58 rushing yards in the last meeting, and the Buckeyes now have fewer secondary options to exploit.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">OSU vs IND Betting Trends<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Indiana snapped Ohio State&#8217;s 30-game winning streak in the series with a win as a 3.5-point underdog in last year&#8217;s Big Ten Championship.<\/li>\n\n\n\n<li>Indiana held Ohio State to 58 rushing yards in that meeting.<\/li>\n\n\n\n<li>Indiana is 9-0 straight up with an average margin of victory of 27.2 points since that game.<\/li>\n\n\n\n<li>Indiana&#8217;s wins during that stretch include Alabama, Oregon, Miami (Fla.) and Nebraska.<\/li>\n\n\n\n<li>Ohio State is 5-2 since the loss to Indiana, with losses to Miami (Fla.) and Texas.<\/li>\n\n\n\n<li>Ohio State is drawing 99 percent of the spread money and 80 percent of the tickets, yet the line has dropped from 4 to 3.5.<\/li>\n\n\n\n<li>The over is drawing 83 percent of the money, but the under at 51.5 is priced at -120.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">OSU vs IND Key Injuries and Notes<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Jeremiah Smith had eight catches for 144 yards in last year&#8217;s meeting.<\/li>\n\n\n\n<li>Smith caught 11 passes against Iowa, more than the rest of Ohio State&#8217;s roster combined.<\/li>\n\n\n\n<li>Julian Sayin threw only 11 passes not targeted toward Smith against Maryland.<\/li>\n\n\n\n<li>Ohio State has not found a reliable second receiver since Carnell Tate&#8217;s departure.<\/li>\n\n\n\n<li>Indiana&#8217;s offense appears to be a step behind last year&#8217;s championship unit.<\/li>\n\n\n\n<li>Indiana is playing at home after a road win at Nebraska.<\/li>\n\n\n\n<li>Check final injury reports before kickoff for updates on both rosters.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Ohio State vs Indiana ATS and Total Picks<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Indiana +3.5 Spread Pick<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Indiana beat Ohio State as a 3.5-point underdog on a neutral field last year, and now the Hoosiers get the same number at home. Since that game, Indiana has won nine straight by an average of more than 27 points, while Ohio State has lost twice. The Buckeyes&#8217; offense has become heavily dependent on Jeremiah Smith, and Curt Cignetti is the right coach to scheme against that. With nearly all of the money on Ohio State failing to push the line higher, Indiana +3.5 is the play.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Pick:<\/strong> Indiana +3.5 (-112)<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">OSU vs IND Under Pick<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Both offenses come with question marks. Indiana&#8217;s attack appears to be a step behind last year&#8217;s version, and Ohio State is relying almost entirely on one receiver. Last year&#8217;s meeting featured an Indiana defense that held the Buckeyes to 58 rushing yards, and a similar effort would make it difficult for Ohio State to sustain drives. The market has priced the under at -120 at 51.5 despite heavy public over support, which points to a game played closer to the vest.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Pick:<\/strong> Under 51.5 (-120)<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Ohio State vs Indiana Best Bets<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Best Bet:<\/strong> Indiana +3.5 (-112)<\/li>\n\n\n\n<li><strong>Moneyline:<\/strong> Indiana to win outright<\/li>\n\n\n\n<li><strong>Total:<\/strong> Under 51.5 (-120)<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Indiana with the points is the strongest play. The Hoosiers have home field, a proven game plan against this opponent and a nine-game winning streak, while Ohio State has become predictable on offense. Indiana on the moneyline is also worth a look as a home underdog. The under completes the card given the questions on both offenses.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Final Score Prediction for Ohio State vs Indiana<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Jeremiah Smith makes his share of plays, but Indiana&#8217;s defense limits everyone else around him and keeps Ohio State&#8217;s run game in check once again. The Hoosiers&#8217; offense does just enough to grind out scoring drives, and the home crowd helps Indiana close out another win over the Buckeyes.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Projected Final Score:<\/strong> Indiana 24, Ohio State 20<\/li>\n\n\n\n<li><strong>Moneyline:<\/strong> Indiana wins outright<\/li>\n\n\n\n<li><strong>Spread:<\/strong> Indiana +3.5 (-112) covers<\/li>\n\n\n\n<li><strong>Total:<\/strong> Under 51.5 (-120) cashes with 44 combined points<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Ohio State won 30 straight games against Indiana, and then the streak ended in last year&#8217;s Big Ten Championship. Since that upset in Indianapolis, the Hoosiers have gone 9-0 with an average margin of victory of 27.2 points, beating Alabama, Oregon, Miami (Fla.) and Nebraska along the way. Ohio State, meanwhile, has gone 5-2 and [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":40636,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[14],"tags":[102,101,5240,5241,17389,5243],"class_list":["post-40635","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-college-football","tag-indiana-hoosiers","tag-ohio-state-buckeyes","tag-ohio-state-vs-indiana","tag-ohio-state-vs-indiana-picks","tag-ohio-state-vs-indiana-prediction","tag-ohio-state-vs-indiana-preview"],"basic_html":"\n<p>Ohio State won 30 straight games against Indiana, and then the streak ended in last year's Big Ten Championship. Since that upset in Indianapolis, the Hoosiers have gone 9-0 with an average margin of victory of 27.2 points, beating Alabama, Oregon, Miami (Fla.) and Nebraska along the way. <\/p>\n\n\n\n\n\n<p>Ohio State, meanwhile, has gone 5-2 and is leaning almost entirely on one receiver. Jeremiah Smith is a generational talent, but Curt Cignetti has proven to be a generational coach, and this time the Hoosiers get the Buckeyes at home. <\/p>\n\n\n\n\n\n<p>Our <strong>Ohio State vs Indiana prediction<\/strong> breaks down the rematch, the busy line movement and our picks on the spread, moneyline and total. For more <a href=\"https:\/\/www.wagertalk.com\/free-sports-picks\/college-football\">free college football picks<\/a>, check out the rest of our weekly card.<\/p>\n\n\n\n\n\n<h2 class=\"wp-block-heading\">Ohio State vs Indiana Quick Picks and Prediction<\/h2>\n\n\n\n\n\n<ul class=\"wp-block-list\">\n\n\n\n\n\n<\/ul>\n\n\n\n\n\n<h2 class=\"wp-block-heading\">Odds and Line Movement for Ohio State vs Indiana<\/h2>\n\n\n\n\n\n<p>Ohio State opened as a 4-point road favorite and has bounced between 3 and 3.5 ever since, settling at -3.5. The total has toggled between 50.5 and 51.5 more than a dozen times. Stay on top of every move with our <a href=\"https:\/\/www.wagertalk.com\/odds\">live odds<\/a> page leading up to kickoff.<\/p>\n\n\n\n\n\n<h3 class=\"wp-block-heading\">Opening Odds<\/h3>\n\n\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Team<\/th><th>Spread<\/th><th>Total<\/th><\/tr><\/thead><tbody><tr><td>Ohio State<\/td><td>-4 (-115)<\/td><td>Over 51.5 (-112)<\/td><\/tr><tr><td>Indiana<\/td><td>+4 (-105)<\/td><td>Under 51.5 (-108)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n\n\n<h3 class=\"wp-block-heading\">Current Odds<\/h3>\n\n\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Team<\/th><th>Spread<\/th><th>Total<\/th><\/tr><\/thead><tbody><tr><td>Ohio State<\/td><td>-3.5 (-108)<\/td><td>Over 51.5 (+100)<\/td><\/tr><tr><td>Indiana<\/td><td>+3.5 (-112)<\/td><td>Under 51.5 (-120)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n\n\n<h3 class=\"wp-block-heading\">Line Movement - Spread<\/h3>\n\n\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Date<\/th><th>Ohio State<\/th><th>Indiana<\/th><\/tr><\/thead><tbody><tr><td>10\/13<\/td><td>-3.5 (-108)<\/td><td>+3.5 (-112)<\/td><\/tr><tr><td>10\/12<\/td><td>-3.5 (-105)<\/td><td>+3.5 (-115)<\/td><\/tr><tr><td>10\/11<\/td><td>-3.5 (-110)<\/td><td>+3.5 (-110)<\/td><\/tr><tr><td>10\/11<\/td><td>-3.5 (-108)<\/td><td>+3.5 (-112)<\/td><\/tr><tr><td>10\/11<\/td><td>-3 (-120)<\/td><td>+3 (+100)<\/td><\/tr><tr><td>10\/11<\/td><td>-3 (-118)<\/td><td>+3 (-102)<\/td><\/tr><tr><td>10\/11<\/td><td>-3 (-115)<\/td><td>+3 (-105)<\/td><\/tr><tr><td>10\/11<\/td><td>-3 (-112)<\/td><td>+3 (-108)<\/td><\/tr><tr><td>10\/11<\/td><td>-3.5 (-102)<\/td><td>+3.5 (-118)<\/td><\/tr><tr><td>10\/11<\/td><td>-3.5 (-105)<\/td><td>+3.5 (-115)<\/td><\/tr><tr><td>10\/11<\/td><td>-3.5 (-102)<\/td><td>+3.5 (-118)<\/td><\/tr><tr><td>10\/11<\/td><td>-3 (-120)<\/td><td>+3 (+100)<\/td><\/tr><tr><td>10\/11<\/td><td>-3 (-118)<\/td><td>+3 (-102)<\/td><\/tr><tr><td>10\/11<\/td><td>-3 (-120)<\/td><td>+3 (+100)<\/td><\/tr><tr><td>10\/11<\/td><td>-3.5 (-105)<\/td><td>+3.5 (-115)<\/td><\/tr><tr><td>10\/11<\/td><td>-4 (-105)<\/td><td>+4 (-115)<\/td><\/tr><tr><td>10\/11<\/td><td>-4 (-110)<\/td><td>+4 (-110)<\/td><\/tr><tr><td>10\/11<\/td><td>-4 (-115)<\/td><td>+4 (-105)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n\n\n<p>Ohio State has drawn nearly all of the money from the start, and currently holds 99 percent of the money and 80 percent of the tickets. Yet the line has dropped from 4 to 3.5 and repeatedly tested 3. When a favorite gets that much one-sided support without moving up, it suggests respected money is on the home underdog.<\/p>\n\n\n\n\n\n<h3 class=\"wp-block-heading\">Line Movement - Total<\/h3>\n\n\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Date<\/th><th>Over<\/th><th>Under<\/th><\/tr><\/thead><tbody><tr><td>10\/14<\/td><td>51.5 (+100)<\/td><td>51.5 (-120)<\/td><\/tr><tr><td>10\/14<\/td><td>50.5 (-120)<\/td><td>50.5 (+100)<\/td><\/tr><tr><td>10\/14<\/td><td>51.5 (+100)<\/td><td>51.5 (-120)<\/td><\/tr><tr><td>10\/14<\/td><td>50.5 (-118)<\/td><td>50.5 (-102)<\/td><\/tr><tr><td>10\/13<\/td><td>51.5 (-102)<\/td><td>51.5 (-118)<\/td><\/tr><tr><td>10\/13<\/td><td>50.5 (-118)<\/td><td>50.5 (-102)<\/td><\/tr><tr><td>10\/13<\/td><td>51.5 (+100)<\/td><td>51.5 (-120)<\/td><\/tr><tr><td>10\/12<\/td><td>50.5 (-118)<\/td><td>50.5 (-102)<\/td><\/tr><tr><td>10\/12<\/td><td>51.5 (-105)<\/td><td>51.5 (-115)<\/td><\/tr><tr><td>10\/12<\/td><td>51.5 (-108)<\/td><td>51.5 (-112)<\/td><\/tr><tr><td>10\/12<\/td><td>50.5 (-118)<\/td><td>50.5 (-102)<\/td><\/tr><tr><td>10\/12<\/td><td>50.5 (-115)<\/td><td>50.5 (-105)<\/td><\/tr><tr><td>10\/12<\/td><td>50.5 (-110)<\/td><td>50.5 (-110)<\/td><\/tr><tr><td>10\/12<\/td><td>50.5 (-105)<\/td><td>50.5 (-115)<\/td><\/tr><tr><td>10\/12<\/td><td>50.5 (-112)<\/td><td>50.5 (-108)<\/td><\/tr><tr><td>10\/12<\/td><td>50.5 (-118)<\/td><td>50.5 (-102)<\/td><\/tr><tr><td>10\/12<\/td><td>51.5 (+100)<\/td><td>51.5 (-120)<\/td><\/tr><tr><td>10\/11<\/td><td>51.5 (-110)<\/td><td>51.5 (-110)<\/td><\/tr><tr><td>10\/11<\/td><td>51.5 (-112)<\/td><td>51.5 (-108)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n\n\n<p>The total has been tug-of-war between 50.5 and 51.5. The under drew 100 percent of the money early in the week, while the over now holds 83 percent of the money and 80 percent of the tickets. Even so, the under at 51.5 is priced at -120, showing the market still respects the low side at this number.<\/p>\n\n\n\n\n\n<figure class=\"wp-block-image aligncenter size-large is-resized\"><a href=\"https:\/\/splashsports.com\/wagertalk\"><img src=\"https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2026\/10\/WT-25K-graphic-3-1024x576.png\" alt=\"\" class=\"wp-image-40455\" style=\"width:588px;height:auto\"\/><\/a><\/figure>\n\n\n\n\n\n<h2 class=\"wp-block-heading\">Ohio State vs Indiana Key Matchups and Handicap<\/h2>\n\n\n\n\n\n<h3 class=\"wp-block-heading\">Indiana's Dominant Run Since the Big Ten Title Game<\/h3>\n\n\n\n\n\n<p>Ohio State's 30-game winning streak over Indiana ended in last year's Big Ten Championship, when the Hoosiers won as a 3.5-point underdog in Indianapolis. Indiana's defense held Ohio State to just 58 rushing yards in that game, though Jeremiah Smith still broke free for eight catches and 144 yards.<\/p>\n\n\n\n\n\n<p>Indiana has been nearly untouchable since. The Hoosiers are 9-0 straight up with an average margin of victory of 27.2 points per game, a stretch that includes wins over Alabama, Oregon, Miami (Fla.) and last week's victory at Nebraska. This year's team appears to be a tick behind last year's championship squad, particularly on offense, but home field and a 3.5-point head start with the defending champions help offset those concerns.<\/p>\n\n\n\n\n\n<h3 class=\"wp-block-heading\">Ohio State's Search for a Second Receiver<\/h3>\n\n\n\n\n\n<p>Ohio State is 5-2 since the loss to Indiana, with defeats to Miami (Fla.) and Texas, and an average point differential of 23.9 points per game over that stretch. There are holes to poke in the Buckeyes' resume, and the biggest one is the lack of a second reliable target.<\/p>\n\n\n\n\n\n<p>In last year's meeting, Ohio State had a viable second option in Carnell Tate, who went on to become a top-five draft pick of the Titans. Halfway through this season, the Buckeyes still have not found this year's Tate. In the win over Iowa two weeks ago, Smith caught more passes (11) than the rest of the team combined (9). In last week's win over Maryland, quarterback Julian Sayin threw only 11 passes that were not targeted toward Smith.<\/p>\n\n\n\n\n\n<h3 class=\"wp-block-heading\">Hoosiers Trust Curt Cignetti's Game Plan<\/h3>\n\n\n\n\n\n<p>Smith is unquestionably one of the best wide receiver prospects in recent memory, but if there is any coach in the country to trust with a proper game plan, it is Curt Cignetti. When an offense funnels this much of its production through one player, a well-prepared defense can make life difficult. Cignetti's staff already held Ohio State to 58 rushing yards in the last meeting, and the Buckeyes now have fewer secondary options to exploit.<\/p>\n\n\n\n\n\n<h2 class=\"wp-block-heading\">OSU vs IND Betting Trends<\/h2>\n\n\n\n\n\n<ul class=\"wp-block-list\">\n\n\n\n\n\n\n\n\n\n\n\n<\/ul>\n\n\n\n\n\n<h2 class=\"wp-block-heading\">OSU vs IND Key Injuries and Notes<\/h2>\n\n\n\n\n\n<ul class=\"wp-block-list\">\n\n\n\n\n\n\n\n\n\n\n\n<\/ul>\n\n\n\n\n\n<h2 class=\"wp-block-heading\">Ohio State vs Indiana ATS and Total Picks<\/h2>\n\n\n\n\n\n<h3 class=\"wp-block-heading\">Indiana +3.5 Spread Pick<\/h3>\n\n\n\n\n\n<p>Indiana beat Ohio State as a 3.5-point underdog on a neutral field last year, and now the Hoosiers get the same number at home. Since that game, Indiana has won nine straight by an average of more than 27 points, while Ohio State has lost twice. The Buckeyes' offense has become heavily dependent on Jeremiah Smith, and Curt Cignetti is the right coach to scheme against that. With nearly all of the money on Ohio State failing to push the line higher, Indiana +3.5 is the play.<\/p>\n\n\n\n\n\n<ul class=\"wp-block-list\"><\/ul>\n\n\n\n\n\n<h3 class=\"wp-block-heading\">OSU vs IND Under Pick<\/h3>\n\n\n\n\n\n<p>Both offenses come with question marks. Indiana's attack appears to be a step behind last year's version, and Ohio State is relying almost entirely on one receiver. Last year's meeting featured an Indiana defense that held the Buckeyes to 58 rushing yards, and a similar effort would make it difficult for Ohio State to sustain drives. The market has priced the under at -120 at 51.5 despite heavy public over support, which points to a game played closer to the vest.<\/p>\n\n\n\n\n\n<ul class=\"wp-block-list\"><\/ul>\n\n\n\n\n\n<h2 class=\"wp-block-heading\">Ohio State vs Indiana Best Bets<\/h2>\n\n\n\n\n\n<ul class=\"wp-block-list\">\n\n\n\n<\/ul>\n\n\n\n\n\n<p>Indiana with the points is the strongest play. The Hoosiers have home field, a proven game plan against this opponent and a nine-game winning streak, while Ohio State has become predictable on offense. Indiana on the moneyline is also worth a look as a home underdog. The under completes the card given the questions on both offenses.<\/p>\n\n\n\n\n\n<h2 class=\"wp-block-heading\">Final Score Prediction for Ohio State vs Indiana<\/h2>\n\n\n\n\n\n<p>Jeremiah Smith makes his share of plays, but Indiana's defense limits everyone else around him and keeps Ohio State's run game in check once again. The Hoosiers' offense does just enough to grind out scoring drives, and the home crowd helps Indiana close out another win over the Buckeyes.<\/p>\n\n\n\n\n\n<ul class=\"wp-block-list\">\n\n\n\n\n\n<\/ul>\n","_links":{"self":[{"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/posts\/40635","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/comments?post=40635"}],"version-history":[{"count":1,"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/posts\/40635\/revisions"}],"predecessor-version":[{"id":40637,"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/posts\/40635\/revisions\/40637"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/media\/40636"}],"wp:attachment":[{"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/media?parent=40635"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/categories?post=40635"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/tags?post=40635"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}