{"id":40224,"date":"2026-09-25T07:52:34","date_gmt":"2026-09-25T11:52:34","guid":{"rendered":"https:\/\/www.wagertalk.com\/news\/?p=40224"},"modified":"2026-09-25T07:52:36","modified_gmt":"2026-09-25T11:52:36","slug":"best-home-run-props-today-hr-picks-predictions-for-september-25","status":"publish","type":"post","link":"https:\/\/www.wagertalk.com\/news\/mlb\/best-home-run-props-today-hr-picks-predictions-for-september-25\/","title":{"rendered":"Best MLB Home Run Props Today: HR Picks & Predictions for September 25"},"content":{"rendered":"\n

Looking for the best\u00a0MLB home run props today<\/strong>? WagerTalk has you covered with\u00a0HR picks, predictions and best bets for Friday, September 25<\/strong>, as we break down today\u2019s MLB slate in search of the top hitters to go deep. Check out our latest home run prop picks and betting analysis as we identify potential value across the daily MLB player prop markets.<\/p>\n\n\n\n

Follow WagerTalk all season long for\u00a0MLB home run predictions, player prop picks and\u00a0free MLB picks<\/a><\/strong>\u00a0every day. Check out our\u00a0best MLB home run prop bets today for Friday, September 25!<\/strong><\/p>\n\n\n\n

MLB Home Run Props Today: Best HR Picks, Predictions & Bets<\/h2>\n\n\n\n

Best MLB Home Run Prop Today #1: <\/strong>Bryce Harper (PHI) +400<\/h3>\n\n\n\n

The Phillies still need to do some work if they want to clinch the final NL Wildcard spot as they host the Rays for their final three games of the regular season. <\/p>\n\n\n\n

We\u2019re going to take Bryce Harper for his home run props today with spectacular splits against Rays starter Freddy Peralta. All-time against Peralta, Harper is 5-16 with two doubles and three home runs with the Phillies first baseman slugging .587 against righties including 24 of his 28 total home runs this season. <\/p>\n\n\n\n

Although Peralta hasn\u2019t allowed a home run in each of his last three starts (16.2 IP) two of those three starts came at home. On the season Peralta sports a 5.81 road ERA including 15 of his 23 total home runs he\u2019s given up compared to a 3.53 ERA in home starts. <\/p>\n\n\n\n

He has allowed 17 of his 23 home runs to left handed batters like Harper, and if Peralta happens to not allow a home run to Harper while he\u2019s in the game that\u2019s not a problem with the Rays bullpen unit tied for second most home runs given up in the MLB this season among all bullpens. <\/p>\n\n\n\n

Harper has three combined home runs off Rays relievers Casey Legumina and Steven Matz to let\u2019s take him at +400 to cash his home run props<\/strong> tonight. If you\u2019re looking for other Phillies batters for home run props consider Kyle Schwarber (+250)<\/strong> and Brandon Marsh (+630)<\/strong>.<\/p>\n\n\n\n

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Best MLB Home Run Prop Today #2: <\/strong>Christian Walker (HOU) +390<\/h3>\n\n\n\n

As we head into the final three games of the regular season, the Astros and Rangers are tied atop the AL West. The Astros blasted five home runs in their series opening win against the Athletics last night as these two play once again in Sacramento tonight. <\/p>\n\n\n\n

We\u2019re going to take Christian Walker to cash his home run props tonight as he hit one of those five home runs for Houston last night in that win. <\/p>\n\n\n\n

That was Walker\u2019s 27th home run this season and his 17th on the road hitting .236 and slugging .458 in road games compared to a .209 average and .372 slugging percentage at home. <\/p>\n\n\n\n

He has loved playing the Athletics in general this season hitting .342 and slugging .684 against them including three home runs. Lefty Jacob Lopez makes his final start for the Athletics this season, but has been absolutely brutal as of late sporting a 10.31 ERA across his last four starts including seven home runs given up in just 18.1 innings pitched. <\/p>\n\n\n\n

He has allowed 22 home runs in total this season with 19 of them coming against right handed hitting including a .507 slugging percentage given up compared to a .331 slugging percentage given up to left handed hitters. <\/p>\n\n\n\n

Even if Lopez doesn\u2019t make it far in his start tonight, the Athletics pitching staff has given up the second most home runs since the all-star break and the bullpen is tied for the the second most home runs given up of any bullpen unit in the MLB this season. <\/p>\n\n\n\n

With that, take Walker at +390 to hit his home run props<\/strong> tonight with other Astros batters to consider for home run props being Yordan Alvarez (+310)<\/strong> and Isaac Paredes (+370)<\/strong>.
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