{"id":40168,"date":"2026-09-21T08:01:05","date_gmt":"2026-09-21T12:01:05","guid":{"rendered":"https:\/\/www.wagertalk.com\/news\/?p=40168"},"modified":"2026-09-21T08:01:56","modified_gmt":"2026-09-21T12:01:56","slug":"home-run-props-today-best-hr-picks-bets-for-september-21-2026","status":"publish","type":"post","link":"https:\/\/www.wagertalk.com\/news\/mlb\/home-run-props-today-best-hr-picks-bets-for-september-21-2026\/","title":{"rendered":"MLB Home Run Props Today: Best HR Picks &amp; Bets for September 21, 2026"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Looking for<strong> home run props<\/strong> picks and predictions today? Tons of home runs have been hit this regular season and we&#8217;re ready to pick more winners on Monday! Free home run prop picks come at you compliments of WagerTalk.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Let&#8217;s see if we can beat the books with home run prop bets today with <a href=\"https:\/\/www.wagertalk.com\/free-sports-picks\/mlb\">free MLB picks<\/a> every day at WagerTalk! Here are the best home run prop bets to make for <strong>Monday, September 21!<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Best Home Run Prop Bets &#8211; MLB Free HR Props Picks<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>MLB Home Run Props Best Bet of the Day #1: Coby Mayo (BAL) +390<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">We have a very shortened slate for Monday in the MLB so we\u2019re heading to Baltimore to take Coby Mayo and his home run props with the Orioles looking to bounce back from two straight shutout losses to the Brewers. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Trey Yesavage comes off the IL to start for the Blue Jays with five of his last seven home runs allowed coming on the road. Yesavage has allowed five of his ten total home runs this season to right handed hitters with Mayo slugging .506 at home compared to slugging .443 on the road. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Over the last 15 days Mayo is batting .280 and slugging .660 including five home runs. Since the all-star break he\u2019s slugging .571 compared to a .395 slugging percentage before the break. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">All-time Mayo is 2-5 against Yesavage with a home run that came back on June 5th and is also 2-3 with two home runs against Blue Jays reliever Braydon Fisher. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Although the Orioles are out of post season contention, look for <strong>Mayo to finish out his breakout season strong this week as we\u2019ll take his home run props at +390 odds<\/strong> on Monday at home against Toronto. Other Orioles to consider for home run props today are <strong>Pete Alonso (+340)<\/strong> and <strong>Samuel Basallo (+420)<\/strong>.<\/p>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/wt.buzz\/splashsports\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" width=\"1024\" height=\"576\" data-id=\"40171\" src=\"https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2026\/09\/WTNFLSplashWeek3-1024x576.jpg\" alt=\"\" class=\"wp-image-40171\" srcset=\"https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2026\/09\/WTNFLSplashWeek3-1024x576.jpg 1024w, https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2026\/09\/WTNFLSplashWeek3-300x169.jpg 300w, https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2026\/09\/WTNFLSplashWeek3-768x432.jpg 768w, https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2026\/09\/WTNFLSplashWeek3-1536x864.jpg 1536w, https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2026\/09\/WTNFLSplashWeek3.jpg 1672w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><a href=\"https:\/\/www.wagertalk.com\/add-digital-download-to-cart?data_digitalDownloadID=4243&amp;nc=1\"><img decoding=\"async\" width=\"830\" height=\"690\" data-id=\"40039\" src=\"https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2026\/09\/Screenshot-2026-09-02-at-7.46.17-AM.png\" alt=\"\" class=\"wp-image-40039\" style=\"width:346px;height:auto\" srcset=\"https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2026\/09\/Screenshot-2026-09-02-at-7.46.17-AM.png 830w, https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2026\/09\/Screenshot-2026-09-02-at-7.46.17-AM-300x249.png 300w, https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2026\/09\/Screenshot-2026-09-02-at-7.46.17-AM-768x638.png 768w\" sizes=\"(max-width: 830px) 100vw, 830px\" \/><\/a><\/figure>\n<\/div><\/figure>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\"><\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>MLB <strong>Home Run Prop<\/strong>s Best Bet of the Day #2: Kody Clemens (MIN) +420<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The Twins are now out of playoff contention entering the last week of the MLB season but they\u2019ve enjoyed the breakout of Kody Clemens this season who now has 26 home runs which is seven more than his previous season high set last season. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The Twins and Giants start up a three-game set in San Francisco tonight with righty Blade Tidwell taking the mound for the home team. Tidwell has been pretty good over his past couple outings but he has allowed a home run in back-to-back starts and has struggled mightily against left handed batters this season. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Of the seven home runs he has allowed, six have come against left handed batters while allowing them to bat .265 to go along with a .471 slugging percentage compared to right handed batters allowing just a .176 average and .242 slugging percentage. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Sure, Clemens is a better hitter at home batting .267 compared to a .212 average on the road, but 14 of his 26 home runs have come on the road and 21 of 26 coming against right handed pitchers. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In interleague games this season Clemens is slugging .534 compared to a .432 slugging percentage against AL teams <strong>so let\u2019s take him at +420 odds<\/strong> to hit his home run props tonight. Other Twins batters to look at for home run props includes<strong> Josh Bell<\/strong> and <strong>Royce Lewis (both +560)<\/strong>.<br><\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<div class=\"epyt-video-wrapper\"><div  style=\"display: block; margin: 0px auto;\"  id=\"_ytid_89378\"  width=\"870\" height=\"489\"  data-origwidth=\"870\" data-origheight=\"489\" data-facadesrc=\"https:\/\/www.youtube.com\/embed\/?enablejsapi=1&#038;origin=https:\/\/www.wagertalk.com&#038;list=PLhz4vN97EdvhLDiG6QgiDH1cA7xReWX6P&#038;autoplay=0&#038;cc_load_policy=1&#038;cc_lang_pref=&#038;iv_load_policy=1&#038;loop=0&#038;rel=0&#038;fs=1&#038;playsinline=0&#038;autohide=2&#038;hl=en_US&#038;theme=dark&#038;color=red&#038;controls=1&#038;disablekb=0&#038;\" class=\"__youtube_prefs__ epyt-facade  epyt-is-override  no-lazyload\"><img data-spai-excluded=\"true\" class=\"epyt-facade-poster skip-lazy\" loading=\"lazy\"  alt=\"\u26be\ufe0f Free MLB Picks Today: Your Guide to Winning MLB Bets!\"  data-facadeoembed=\"playlist?list=PLhz4vN97EdvhLDiG6QgiDH1cA7xReWX6P\"  \/><button class=\"epyt-facade-play\" aria-label=\"Play\"><svg data-no-lazy=\"1\" height=\"100%\" version=\"1.1\" viewBox=\"0 0 68 48\" width=\"100%\"><path class=\"ytp-large-play-button-bg\" d=\"M66.52,7.74c-0.78-2.93-2.49-5.41-5.42-6.19C55.79,.13,34,0,34,0S12.21,.13,6.9,1.55 C3.97,2.33,2.27,4.81,1.48,7.74C0.06,13.05,0,24,0,24s0.06,10.95,1.48,16.26c0.78,2.93,2.49,5.41,5.42,6.19 C12.21,47.87,34,48,34,48s21.79-0.13,27.1-1.55c2.93-0.78,4.64-3.26,5.42-6.19C67.94,34.95,68,24,68,24S67.94,13.05,66.52,7.74z\" fill=\"#f00\"><\/path><path d=\"M 45,24 27,14 27,34\" fill=\"#fff\"><\/path><\/svg><\/button><\/div><\/div>\n<\/div><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">Enjoyed the Home Run Prop Bets? Get More MLB Bets at the GoldSheet<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Play Ball! GoldSheet&#8217;s daily MLB betting guide has made its triumphant return. We provide marquee hitter vs pitcher matchup notes, <a href=\"https:\/\/wt.buzz\/rm\" data-type=\"link\" data-id=\"https:\/\/wt.buzz\/rm\" target=\"_blank\" rel=\"noopener\">Ralph Michaels<\/a>&#8216; NRFI first inning guide and two recommended free plays each day. Oh yeah, we forgot to mention the price\u2026FREE! Use the link below each day to access the download.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img decoding=\"async\" width=\"1000\" height=\"550\" src=\"https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2024\/08\/gunnar-henderson-hits-home-run-e1722604182180.jpg\" alt=\"home run prop bets\" class=\"wp-image-30405\" style=\"width:311px;height:auto\" srcset=\"https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2024\/08\/gunnar-henderson-hits-home-run-e1722604182180.jpg 1000w, https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2024\/08\/gunnar-henderson-hits-home-run-e1722604182180-300x165.jpg 300w, https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2024\/08\/gunnar-henderson-hits-home-run-e1722604182180-768x422.jpg 768w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">WagerTalk Live Odds Screen<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">WagerTalk\u2019s <a href=\"https:\/\/www.wagertalk.com\/odds?sport=L5&amp;type=4&amp;cb=0.041518762314237456\" target=\"_blank\" rel=\"noopener\">live odds screen<\/a> features up-to-the-minute lines from a variety of offshore and domestic sports books. Track moneylines, runlines, totals and betting percentages for a variety of domestic and international leagues. Find <a href=\"https:\/\/www.wagertalk.com\/free-sports-picks\/mlb\">free MLB picks<\/a>, even for Home Run prop bets, and odds!<\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><strong>**************************************************<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><span style=\"font-size: 12pt;\">Looking for more free sports picks and sports betting tips?<\/span> Go beyond the anytime touchdown scorer picks!<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><span style=\"font-size: 12pt;\"><strong>Latest Betting Odds and Public Action: <\/strong><a href=\"https:\/\/wt.buzz\/odds\" target=\"_blank\" rel=\"noopener\">Vegas lines<\/a> updated in real time, including who the public is betting on<\/span> and anytime touchdown scorer odds.<\/li>\n\n\n\n<li><strong style=\"font-size: 12pt;\">Last Minute Handicapping Advice<\/strong><span style=\"font-size: 12pt;\">: Check out our extensive library of <\/span><a style=\"font-size: 12pt;\" href=\"https:\/\/www.wagertalk.com\/sports-betting-guide\" target=\"_blank\" rel=\"noopener\">handicapping tips<\/a><span style=\"font-size: 12pt;\"> and advice from professional Vegas handicappers (we also recommend taking the time to look over our <\/span><a style=\"font-size: 12pt;\" href=\"https:\/\/www.wagertalk.com\/videos\" target=\"_blank\" rel=\"noopener\">sports betting tips video library<\/a><span style=\"font-size: 12pt;\">)<\/span><\/li>\n\n\n\n<li><strong style=\"font-size: 12pt;\">Want an expert opinion?<\/strong><span style=\"font-size: 12pt;\"> Check out the latest <\/span><a href=\"https:\/\/www.wagertalk.com\/free-sports-picks\" target=\"_blank\" rel=\"noreferrer noopener\">Free Sports Picks<\/a><span style=\"font-size: 12pt;\"> and <\/span><a href=\"https:\/\/www.wagertalk.com\/picks\" target=\"_blank\" rel=\"noreferrer noopener\">Best Bets<\/a><span style=\"font-size: 12pt;\"> from our team of expert sports handicappers.<\/span><\/li>\n<\/ul>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><em>Make sure to bookmark all the above!<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Looking for home run props picks and predictions today? Tons of home runs have been hit this regular season and we&#8217;re ready to pick more winners on Monday! Free home run prop picks come at you compliments of WagerTalk. Let&#8217;s see if we can beat the books with home run prop bets today with free [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":40169,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[5000,16170,16596,895,2479,835,1196,16674],"class_list":["post-40168","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-mlb","tag-best-home-run-props","tag-best-home-run-props-tonight","tag-coby-mayo","tag-home-run-picks","tag-home-run-predictions","tag-home-run-props","tag-home-run-props-tonight","tag-kody-clemens"],"basic_html":"\n<p>Looking for<strong> home run props<\/strong> picks and predictions today? Tons of home runs have been hit this regular season and we're ready to pick more winners on Monday! Free home run prop picks come at you compliments of WagerTalk.<\/p>\n\n\n\n\n\n<p>Let's see if we can beat the books with home run prop bets today with <a href=\"https:\/\/www.wagertalk.com\/free-sports-picks\/mlb\">free MLB picks<\/a> every day at WagerTalk! Here are the best home run prop bets to make for <strong>Monday, September 21!<\/strong><\/p>\n\n\n\n\n\n<h2 class=\"wp-block-heading\">Best Home Run Prop Bets - MLB Free HR Props Picks<\/h2>\n\n\n\n\n\n<h3 class=\"wp-block-heading\"><strong>MLB Home Run Props Best Bet of the Day #1: Coby Mayo (BAL) +390<\/strong><\/h3>\n\n\n\n\n\n<p>We have a very shortened slate for Monday in the MLB so we\u2019re heading to Baltimore to take Coby Mayo and his home run props with the Orioles looking to bounce back from two straight shutout losses to the Brewers. <\/p>\n\n\n\n\n\n<p>Trey Yesavage comes off the IL to start for the Blue Jays with five of his last seven home runs allowed coming on the road. Yesavage has allowed five of his ten total home runs this season to right handed hitters with Mayo slugging .506 at home compared to slugging .443 on the road. <\/p>\n\n\n\n\n\n<p>Over the last 15 days Mayo is batting .280 and slugging .660 including five home runs. Since the all-star break he\u2019s slugging .571 compared to a .395 slugging percentage before the break. <\/p>\n\n\n\n\n\n<p>All-time Mayo is 2-5 against Yesavage with a home run that came back on June 5th and is also 2-3 with two home runs against Blue Jays reliever Braydon Fisher. <\/p>\n\n\n\n\n\n<p>Although the Orioles are out of post season contention, look for <strong>Mayo to finish out his breakout season strong this week as we\u2019ll take his home run props at +390 odds<\/strong> on Monday at home against Toronto. Other Orioles to consider for home run props today are <strong>Pete Alonso (+340)<\/strong> and <strong>Samuel Basallo (+420)<\/strong>.<\/p>\n\n\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped\">\n\n<\/figure>\n\n\n\n\n\n<div class=\"wp-block-columns\"><\/div>\n\n\n\n\n\n<h3 class=\"wp-block-heading\"><strong>MLB <strong>Home Run Prop<\/strong>s Best Bet of the Day #2: Kody Clemens (MIN) +420<\/strong><\/h3>\n\n\n\n\n\n<p>The Twins are now out of playoff contention entering the last week of the MLB season but they\u2019ve enjoyed the breakout of Kody Clemens this season who now has 26 home runs which is seven more than his previous season high set last season. <\/p>\n\n\n\n\n\n<p>The Twins and Giants start up a three-game set in San Francisco tonight with righty Blade Tidwell taking the mound for the home team. Tidwell has been pretty good over his past couple outings but he has allowed a home run in back-to-back starts and has struggled mightily against left handed batters this season. <\/p>\n\n\n\n\n\n<p>Of the seven home runs he has allowed, six have come against left handed batters while allowing them to bat .265 to go along with a .471 slugging percentage compared to right handed batters allowing just a .176 average and .242 slugging percentage. <\/p>\n\n\n\n\n\n<p>Sure, Clemens is a better hitter at home batting .267 compared to a .212 average on the road, but 14 of his 26 home runs have come on the road and 21 of 26 coming against right handed pitchers. <\/p>\n\n\n\n\n\n<p>In interleague games this season Clemens is slugging .534 compared to a .432 slugging percentage against AL teams <strong>so let\u2019s take him at +420 odds<\/strong> to hit his home run props tonight. Other Twins batters to look at for home run props includes<strong> Josh Bell<\/strong> and <strong>Royce Lewis (both +560)<\/strong>.<br><\/p>\n\n\n\n\n\n\n\n\n\n<h3 class=\"wp-block-heading\">Enjoyed the Home Run Prop Bets? Get More MLB Bets at the GoldSheet<\/h3>\n\n\n\n\n\n<p>Play Ball! GoldSheet's daily MLB betting guide has made its triumphant return. We provide marquee hitter vs pitcher matchup notes, <a href=\"https:\/\/wt.buzz\/rm\" data-type=\"link\" data-id=\"https:\/\/wt.buzz\/rm\">Ralph Michaels<\/a>' NRFI first inning guide and two recommended free plays each day. Oh yeah, we forgot to mention the price\u2026FREE! Use the link below each day to access the download.<\/p>\n\n\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img src=\"https:\/\/www.wagertalk.com\/news\/wp-content\/uploads\/2024\/08\/gunnar-henderson-hits-home-run-e1722604182180.jpg\" alt=\"home run prop bets\" class=\"wp-image-30405\" style=\"width:311px;height:auto\"\/><\/figure>\n\n\n\n\n\n<h2 class=\"wp-block-heading\">WagerTalk Live Odds Screen<\/h2>\n\n\n\n\n\n<p>WagerTalk\u2019s <a href=\"https:\/\/www.wagertalk.com\/odds?sport=L5&amp;type=4&amp;cb=0.041518762314237456\" target=\"_blank\" rel=\"noopener\">live odds screen<\/a> features up-to-the-minute lines from a variety of offshore and domestic sports books. Track moneylines, runlines, totals and betting percentages for a variety of domestic and international leagues. Find <a href=\"https:\/\/www.wagertalk.com\/free-sports-picks\/mlb\">free MLB picks<\/a>, even for Home Run prop bets, and odds!<\/p>\n\n\n\n\n\n<p class=\"has-text-align-center\"><strong>**************************************************<\/strong><\/p>\n\n\n\n\n\n<p><strong><span style=\"font-size: 12pt;\">Looking for more free sports picks and sports betting tips?<\/span> Go beyond the anytime touchdown scorer picks!<\/strong><\/p>\n\n\n\n\n\n<ul class=\"wp-block-list\">\n\n\n\n<\/ul>\n\n\n\n\n\n<p class=\"has-text-align-center\"><em>Make sure to bookmark all the above!<\/em><\/p>\n","_links":{"self":[{"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/posts\/40168","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/comments?post=40168"}],"version-history":[{"count":2,"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/posts\/40168\/revisions"}],"predecessor-version":[{"id":40172,"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/posts\/40168\/revisions\/40172"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/media\/40169"}],"wp:attachment":[{"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/media?parent=40168"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/categories?post=40168"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.wagertalk.com\/news\/wp-json\/wp\/v2\/tags?post=40168"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}