Best Home Run Prop Bets Today – HR Prop Picks For Thursday, September 25
The 2025 MLB season is here, and who doesn’t love home run prop bets? Tons of home runs have already been hit this season and we’re ready to pick more winners in 2025! Free home run prop picks each day come at you compliments of WagerTalk.
Let’s see if we can beat the books with home run prop bets on Thursday! You can find free MLB picks every day at WagerTalk! Here are the best home run prop bets to make for Thursday, September 25!
Best Home Run Prop Bets – MLB Free HR Props Picks
Jose Altuve (HOU) +500
The Astros need to stop the bleeding before it costs them a playoff berth after leading the AL West for much of the 2025 season.
They attempt to snap a five-game losing streak in Sacramento taking on the Athletics for the final time this season.
J.T. Ginn takes the mound for the Athletics today posting a 5.98 home ERA while allowing 12 home runs in 43.2 innings pitched and five home runs in 25.1 innings pitched during day starts.
We’re going to look to Houston’s leader Jose Altuve to get them out of this slump and take him to hit his home run prop today.
He doesn’t have a hit off Ginn in five at bats all-time but against the Athletics this season he’s slugging .571 with his four home runs against them the most he’s had against any single team this season.
Altuve is a better batter at home than on the road but Sutter Health Park has allowed the third most home runs this season of any stadium in the MLB.
If the season ended today the Astros would not make the playoffs making their last four games of the season must win.
Take Altuve at +500 odds to hit his home run prop today with other Astros batters to consider for a home run prop are Christian Walker (+360) and Jesus Sanchez (+420).
MLB HR Props Best Bet of the Day #2: Vladimir Guerrero Jr. (TOR) +440
Bryan Bello has given up a home run in back to back home starts and how gets the road start taking on the Blue Jays in Toronto.
Bello has given up eight of his 16 home runs on the road in 59.2 innings pitched compared to the other eight at home coming in 102 innings pitched.
Vladimir Guerrero Jr. is 11-27 with four doubles and two home runs all time off Bello as we’ll take him to hit his home run prop tonight.
Sure, the Blue Jays first baseman has gone hitless in the first two games of this series, but he does have three home runs against the Red Sox this season which is the most against any single opponent in 2025. Guerrero Jr. is batting .341 in September which is currently his highest for a single month in 2025 as well.
It has been a down year as far as power is concerned for Guerrero Jr. with his 23 home runs being the least he has had in a single season since his rookie year in 2019 where he hit 15 home runs in 123 games.
With the Blue Jays still having a shot at the AL East Championship, take Guerrero Jr. to hit his home run prop tonight at +440 odds with other Blue Jays batters to look at for a home run prop includes George Springer (+420) and Addison Barger (+480).
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